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Protein-nucleic acid interaction


This category describes methods for the analysis of protein-nucleic acid interactions including footprinting, interference, cross-linking, fluorescence techniques, one- and tri-hybrid strategies, in vivo methods and analysis of mutants.


Citations 1-10 of 140 total displayed.

Most recent content

Methods Online
A generalized conformational energy function of DNA derived from molecular dynamics simulations
Satoshi Yamasaki, Tohru Terada, Kentaro Shimizu, Hidetoshi Kono, and Akinori Sarai
Nucleic Acids Res. 2009; 37: e135. [Abstract] [Full text] [Print PDF]  

Nucleic Acid Enzymes
High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display
Jordan Jarjour, Hoku West-Foyle, Michael T. Certo, Christopher G. Hubert, Lindsey Doyle, Melissa M. Getz, Barry L. Stoddard, and Andrew M. Scharenberg
Nucleic Acids Res. 2009; 37: 6871-6880. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Methods Online
cDNA display: a novel screening method for functional disulfide-rich peptides by solid-phase synthesis and stabilization of mRNA–protein fusions
Junichi Yamaguchi, Mohammed Naimuddin, Manish Biyani, Toru Sasaki, Masayuki Machida, Tai Kubo, Takashi Funatsu, Yuzuru Husimi, and Naoto Nemoto
Nucleic Acids Res. 2009; 37: e108. [Abstract] [Full text] [Print PDF]  

Gene Regulation, Chromatin and Epigenetics
Analysis of individual remodeled nucleosomes reveals decreased histone–DNA contacts created by hSWI/SNF
Karim Bouazoune, Tina B. Miranda, Peter A. Jones, and Robert E. Kingston
Nucleic Acids Res. 2009; 37: 5279-5294. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Nucleic Acid Enzymes
Dissecting protein-induced DNA looping dynamics in real time
Niels Laurens, Stuart R. W. Bellamy, August F. Harms, Yana S. Kovacheva, Stephen E. Halford, and Gijs J. L. Wuite
Nucleic Acids Res. 2009; 37: 5454-5464. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information
Wenwei Xiong, Tonghua Li, Kai Chen, and Kailin Tang
Nucleic Acids Res. 2009; 37: 5632-5640. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays
Andrew J. Bonham, Thorsten Neumann, Matthew Tirrell, and Norbert O. Reich
Nucleic Acids Res. 2009; 37: e94. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Assessment of the optimization of affinity and specificity at protein–DNA interfaces
Justin Ashworth and David Baker
Nucleic Acids Res. 2009; 37: e73. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications
Pedro Rodriguez-Collazo, Sanford H. Leuba, and Jordanka Zlatanova
Nucleic Acids Res. 2009; 37: e81. [Abstract] [Full text] [Print PDF]  

Methods Online
Tissue-specific regulatory network extractor (TS-REX): a database and software resource for the tissue and cell type-specific investigation of transcription factor-gene networks
Federico Colecchia, Denise Kottwitz, Mandy Wagner, Cosima V. Pfenninger, Gerald Thiel, Ingo Tamm, Carsten Peterson, and Ulrike A. Nuber
Nucleic Acids Res. 2009; 37: e82. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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