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Protein-nucleic acid interaction


This category describes methods for the analysis of protein-nucleic acid interactions including footprinting, interference, cross-linking, fluorescence techniques, one- and tri-hybrid strategies, in vivo methods and analysis of mutants.

Citations 1-10 of 105 total displayed.

Most recent content

Methods Online
Detecting cis-regulatory binding sites for cooperatively binding proteins
Liesbeth van Oeffelen, Pierre Cornelis, Wouter Van Delm, Fedor De Ridder, Bart De Moor, and Yves Moreau
Nucleic Acids Res. 2008; 36: e46. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Molecular Biology
Single-molecule manipulation reveals supercoiling-dependent modulation of lac repressor-mediated DNA looping
Davide Normanno, Francesco Vanzi, and Francesco Saverio Pavone
Nucleic Acids Res. 2008; 36: 2505-2513. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Genomics
A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system
Marcus B. Noyes, Xiangdong Meng, Atsuya Wakabayashi, Saurabh Sinha, Michael H. Brodsky, and Scot A. Wolfe
Nucleic Acids Res. 2008; 36: 2547-2560. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Computational Biology
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
Dmitry B. Veprintsev and Alan R. Fersht
Nucleic Acids Res. 2008; 36: 1589-1598. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Microplate-based chromatin immunoprecipitation method, Matrix ChIP: a platform to study signaling of complex genomic events
Steve Flanagin, Joel D. Nelson, David G. Castner, Oleg Denisenko, and Karol Bomsztyk
Nucleic Acids Res. 2008; 36: e17. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Molecular Biology
Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination
Jeffrey B. Doyon and David R. Liu
Nucleic Acids Res. 2007; 35: 5851-5860. [Abstract] [Full text] [Print PDF]  

Methods Online
Analytical biochemistry of DNA–protein assemblies from crude cell extracts
Nadia Hégarat, Gildas Mouta Cardoso, Filippo Rusconi, Jean-Christophe François, and Danièle Praseuth
Nucleic Acids Res. 2007; 35: e92. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
General transfer matrix formalism to calculate DNA–protein–drug binding in gene regulation: application to OR operator of phage {lambda}
Vladimir B. Teif
Nucleic Acids Res. 2007; 35: e80. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method
Xiangdong Meng, Stacey Thibodeau-Beganny, Tao Jiang, J. Keith Joung, and Scot A. Wolfe
Nucleic Acids Res. 2007; 35: e81. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach
Hugh P. Morgan, Peter Estibeiro, Martin A. Wear, Klaas E.A. Max, Udo Heinemann, Liza Cubeddu, Maurice P. Gallagher, Peter J. Sadler, and Malcolm D. Walkinshaw
Nucleic Acids Res. 2007; 35: e75. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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