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Protein-nucleic acid interaction


This category describes methods for the analysis of protein-nucleic acid interactions including footprinting, interference, cross-linking, fluorescence techniques, one- and tri-hybrid strategies, in vivo methods and analysis of mutants.


Citations 1-10 of 133 total displayed.

Most recent content

Methods Online
Assessment of the optimization of affinity and specificity at protein–DNA interfaces
Justin Ashworth and David Baker
Nucleic Acids Res. 2009; 37: e73. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications
Pedro Rodriguez-Collazo, Sanford H. Leuba, and Jordanka Zlatanova
Nucleic Acids Res. 2009; 37: e81. [Abstract] [Full text] [Print PDF]  

Methods Online
Tissue-specific regulatory network extractor (TS-REX): a database and software resource for the tissue and cell type-specific investigation of transcription factor-gene networks
Federico Colecchia, Denise Kottwitz, Mandy Wagner, Cosima V. Pfenninger, Gerald Thiel, Ingo Tamm, Carsten Peterson, and Ulrike A. Nuber
Nucleic Acids Res. 2009; 37: e82. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Methods Online
Selection of aptamers for a protein target in cell lysate and their application to protein purification
Sahar Javaherian, Michael U. Musheev, Mirzo Kanoatov, Maxim V. Berezovski, and Sergey N. Krylov
Nucleic Acids Res. 2009; 37: e62. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex
Jose Luis Ortega-Roldan, Malene Ringkjøbing Jensen, Bernhard Brutscher, Ana I. Azuaga, Martin Blackledge, and Nico A. J. van Nuland
Nucleic Acids Res. 2009; 37: e70. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Composite RNA aptamers as functional mimics of proteins
Daiying Xu and Hua Shi
Nucleic Acids Res. 2009; 37: e71. [Abstract] [Full text] [Print PDF]  

Computational Biology
Engineering transcription factors with novel DNA-binding specificity using comparative genomics
Tasha A. Desai, Dmitry A. Rodionov, Mikhail S. Gelfand, Eric J. Alm, and Christopher V. Rao
Nucleic Acids Res. 2009; 37: 2493-2503. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
DNA sampling: a method for probing protein binding at specific loci on bacterial chromosomes
Matej Butala, Stephen J. W. Busby, and David J. Lee
Nucleic Acids Res. 2009; 37: e37. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
COTRASIF: conservation-aided transcription-factor-binding site finder
Bogdan Tokovenko, Rostyslav Golda, Oleksiy Protas, Maria Obolenskaya, and Anna El'skaya
Nucleic Acids Res. 2009; 37: e49. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Nucleic Acid Enzymes
Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
Kelly L. Sanders, Lucy E. Catto, Stuart R. W. Bellamy, and Stephen E. Halford
Nucleic Acids Res. 2009; 37: 2105-2115. [Abstract] [Full text] [Print PDF]  

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