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Protein-nucleic acid interaction


This category describes methods for the analysis of protein-nucleic acid interactions including footprinting, interference, cross-linking, fluorescence techniques, one- and tri-hybrid strategies, in vivo methods and analysis of mutants.


Citations 11-20 of 140 total displayed.

Past content

Methods Online
Selection of aptamers for a protein target in cell lysate and their application to protein purification
Sahar Javaherian, Michael U. Musheev, Mirzo Kanoatov, Maxim V. Berezovski, and Sergey N. Krylov
Nucleic Acids Res. 2009; 37: e62. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex
Jose Luis Ortega-Roldan, Malene Ringkjøbing Jensen, Bernhard Brutscher, Ana I. Azuaga, Martin Blackledge, and Nico A. J. van Nuland
Nucleic Acids Res. 2009; 37: e70. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Composite RNA aptamers as functional mimics of proteins
Daiying Xu and Hua Shi
Nucleic Acids Res. 2009; 37: e71. [Abstract] [Full text] [Print PDF]  

Computational Biology
Engineering transcription factors with novel DNA-binding specificity using comparative genomics
Tasha A. Desai, Dmitry A. Rodionov, Mikhail S. Gelfand, Eric J. Alm, and Christopher V. Rao
Nucleic Acids Res. 2009; 37: 2493-2503. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
DNA sampling: a method for probing protein binding at specific loci on bacterial chromosomes
Matej Butala, Stephen J. W. Busby, and David J. Lee
Nucleic Acids Res. 2009; 37: e37. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
COTRASIF: conservation-aided transcription-factor-binding site finder
Bogdan Tokovenko, Rostyslav Golda, Oleksiy Protas, Maria Obolenskaya, and Anna El'skaya
Nucleic Acids Res. 2009; 37: e49. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Nucleic Acid Enzymes
Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands
Kelly L. Sanders, Lucy E. Catto, Stuart R. W. Bellamy, and Stephen E. Halford
Nucleic Acids Res. 2009; 37: 2105-2115. [Abstract] [Full text] [Print PDF]  

Methods Online
Mutually exclusive STAT1 modifications identified by Ubc9/substrate dimerization-dependent SUMOylation
Susan Zimnik, Matthias Gaestel, and Rainer Niedenthal
Nucleic Acids Res. 2009; 37: e30. [Abstract] [Full text] [Print PDF]  

Methods Online
Sensing peptide–oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein
Volodymyr V. Shvadchak, Andrey S. Klymchenko, Hugues de Rocquigny, and Yves Mély
Nucleic Acids Res. 2009; 37: e25. [Abstract] [Full text] [Print PDF]  

Methods Online
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape
Christopher G. Knight, Mark Platt, William Rowe, David C. Wedge, Farid Khan, Philip J. R. Day, Andy McShea, Joshua Knowles, and Douglas B. Kell
Nucleic Acids Res. 2009; 37: e6. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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