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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 1-10 of 355 total displayed.

Most recent content

Methods Online
VENN, a tool for titrating sequence conservation onto protein structures
Jay Vyas, Michael R. Gryk, and Martin R. Schiller
Nucleic Acids Res. 2009; 37: e124. [Abstract] [Full text] [Print PDF]  

Methods Online
SubpathwayMiner: a software package for flexible identification of pathways
Chunquan Li, Xia Li, Yingbo Miao, Qianghu Wang, Wei Jiang, Chun Xu, Jing Li, Junwei Han, Fan Zhang, Binsheng Gong, and Liangde Xu
Nucleic Acids Res. 2009; 37: e131. [Abstract] [Full text] [Print PDF]  

Computational Biology
Detecting species-site dependencies in large multiple sequence alignments
Roland Schwarz, Philipp N. Seibel, Sven Rahmann, Christoph Schoen, Mirja Huenerberg, Clemens Müller-Reible, Thomas Dandekar, Rachel Karchin, Jörg Schultz, and Tobias Müller
Nucleic Acids Res. 2009; 37: 5959-5968. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Combinatorial network of primary and secondary microRNA-driven regulatory mechanisms
Kang Tu, Hui Yu, You-Jia Hua, Yuan-Yuan Li, Lei Liu, Lu Xie, and Yi-Xue Li
Nucleic Acids Res. 2009; 37: 5969-5980. [Abstract] [Full text] [Print PDF] [ Supplementary Data ] [ Supplementary Data ]  

Structural Biology
Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G·C·G·C tetrad
Kah Wai Lim, Patrizia Alberti, Aurore Guédin, Laurent Lacroix, Jean-François Riou, Nicola J. Royle, Jean-Louis Mergny, and Anh Tuân Phan
Nucleic Acids Res. 2009; 37: 6239-6248. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Multiplex primer prediction software for divergent targets
Shea N. Gardner, Amy L. Hiddessen, Peter L. Williams, Christine Hara, Mark C. Wagner, and Bill W. Colston, Jr
Nucleic Acids Res. 2009; 37: 6291-6304. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Internal standard-based analysis of microarray data. Part 1: analysis of differential gene expressions
Igor Dozmorov and Ivan Lefkovits
Nucleic Acids Res. 2009; 37: 6323-6339. [Abstract] [Full text] [Print PDF]  

Past content

Methods Online
Detection of single nucleotide variations in expressed exons of the human genome using RNA-Seq
Iouri Chepelev, Gang Wei, Qingsong Tang, and Keji Zhao
Nucleic Acids Res. 2009; 37: e106. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
ORMA: a tool for identification of species-specific variations in 16S rRNA gene and oligonucleotides design
Marco Severgnini, Paola Cremonesi, Clarissa Consolandi, Giada Caredda, Gianluca De Bellis, and Bianca Castiglioni
Nucleic Acids Res. 2009; 37: e109. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Extracting transcription factor targets from ChIP-Seq data
Geetu Tuteja, Peter White, Jonathan Schug, and Klaus H. Kaestner
Nucleic Acids Res. 2009; 37: e113. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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