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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 11-20 of 359 total displayed.

Past content

Computational Biology
Internal standard-based analysis of microarray data. Part 1: analysis of differential gene expressions
Igor Dozmorov and Ivan Lefkovits
Nucleic Acids Res. 2009; 37: 6323-6339. [Abstract] [Full text] [Print PDF]  

Methods Online
Detection of single nucleotide variations in expressed exons of the human genome using RNA-Seq
Iouri Chepelev, Gang Wei, Qingsong Tang, and Keji Zhao
Nucleic Acids Res. 2009; 37: e106. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
ORMA: a tool for identification of species-specific variations in 16S rRNA gene and oligonucleotides design
Marco Severgnini, Paola Cremonesi, Clarissa Consolandi, Giada Caredda, Gianluca De Bellis, and Bianca Castiglioni
Nucleic Acids Res. 2009; 37: e109. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Extracting transcription factor targets from ChIP-Seq data
Geetu Tuteja, Peter White, Jonathan Schug, and Klaus H. Kaestner
Nucleic Acids Res. 2009; 37: e113. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Discovery of protein–DNA interactions by penalized multivariate regression
Leonid Zamdborg and Ping Ma
Nucleic Acids Res. 2009; 37: 5246-5254. [Abstract] [Full text] [Print PDF]  

Computational Biology
Detection of genomic islands via segmental genome heterogeneity
Aaron J. Arvey, Rajeev K. Azad, Alpan Raval, and Jeffrey G. Lawrence
Nucleic Acids Res. 2009; 37: 5255-5266. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Genomics
Integrated study of copy number states and genotype calls using high-density SNP arrays
Wei Sun, Fred A. Wright, Zhengzheng Tang, Silje H. Nordgard, Peter Van Loo, Tianwei Yu, Vessela N. Kristensen, and Charles M. Perou
Nucleic Acids Res. 2009; 37: 5365-5377. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Diversity and dispersal of a ubiquitous protein family: acyl-CoA dehydrogenases
Yao-Qing Shen, B. Franz Lang, and Gertraud Burger
Nucleic Acids Res. 2009; 37: 5619-5631. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Local combinational variables: an approach used in DNA-binding helix-turn-helix motif prediction with sequence information
Wenwei Xiong, Tonghua Li, Kai Chen, and Kailin Tang
Nucleic Acids Res. 2009; 37: 5632-5640. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
From Corynebacterium glutamicum to Mycobacterium tuberculosis—towards transfers of gene regulatory networks and integrated data analyses with MycoRegNet
Justina Krawczyk, Thomas A. Kohl, Alexander Goesmann, Jörn Kalinowski, and Jan Baumbach
Nucleic Acids Res. 2009; 37: e97. [Abstract] [Full text] [Print PDF]  

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