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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 191-200 of 359 total displayed.

Past content

Articles
Comparative genomics analysis of NtcA regulons in cyanobacteria: regulation of nitrogen assimilation and its coupling to photosynthesis
Zhengchang Su, Victor Olman, Fenglou Mao, and Ying Xu
Nucleic Acids Res. 2005; 33: 5156-5171. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
The Gumbel pre-factor k for gapped local alignment can be estimated from simulations of global alignment
Sergey Sheetlin, Yonil Park, and John L. Spouge
Nucleic Acids Res. 2005; 33: 4987-4994. [Abstract] [Full text] [Print PDF]  

Articles
A thermodynamic approach to designing structure-free combinatorial DNA word sets
Michael R. Shortreed, Seo Bong Chang, DongGee Hong, Maggie Phillips, Bridget Campion, Dan C. Tulpan, Mirela Andronescu, Anne Condon, Holger H. Hoos, and Lloyd M. Smith
Nucleic Acids Res. 2005; 33: 4965-4977. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Scoring schemes of palindrome clusters for more sensitive prediction of replication origins in herpesviruses
David S. H. Chew, Kwok Pui Choi, and Ming-Ying Leung
Nucleic Acids Res. 2005; 33: e134. [Abstract] [Full text] [Print PDF]  

Methods Online
Detecting seeded motifs in DNA sequences
Cinzia Pizzi, Stefania Bortoluzzi, Andrea Bisognin, Alessandro Coppe, and Gian Antonio Danieli
Nucleic Acids Res. 2005; 33: e135. [Abstract] [Full text] [Print PDF]  

Articles
Identifying cooperative transcriptional regulations using protein–protein interactions
Nobuyoshi Nagamine, Yuji Kawada, and Yasubumi Sakakibara
Nucleic Acids Res. 2005; 33: 4828-4837. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Using multiple alignments to improve seeded local alignment algorithms
Jason Flannick and Serafim Batzoglou
Nucleic Acids Res. 2005; 33: 4563-4577. [Abstract] [Full text] [Print PDF]  

Articles
GANA—a genetic algorithm for NMR backbone resonance assignment
Hsin-Nan Lin, Kun-Pin Wu, Jia-Ming Chang, Ting-Yi Sung, and Wen-Lian Hsu
Nucleic Acids Res. 2005; 33: 4593-4601. [Abstract] [Full text] [Print PDF]  

Articles
Computer identification of snoRNA genes using a Mammalian Orthologous Intron Database
Alexei Fedorov, Jesse Stombaugh, Michael W. Harr, Saihua Yu, Lorena Nasalean, and Valery Shepelev
Nucleic Acids Res. 2005; 33: 4578-4583. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Refinement of docked protein–ligand and protein–DNA structures using low frequency normal mode amplitude optimization
Erik Lindahl and Marc Delarue
Nucleic Acids Res. 2005; 33: 4496-4506. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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