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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 201-210 of 359 total displayed.

Past content

Articles
Predicting specificity-determining residues in two large eukaryotic transcription factor families
Jason E. Donald and Eugene I. Shakhnovich
Nucleic Acids Res. 2005; 33: 4455-4465. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
miBLAST: scalable evaluation of a batch of nucleotide sequence queries with BLAST
You Jung Kim, Andrew Boyd, Brian D. Athey, and Jignesh M. Patel
Nucleic Acids Res. 2005; 33: 4335-4344. [Abstract] [Full text] [Print PDF]  

Articles
Uracil content of 16S rRNA of thermophilic and psychrophilic prokaryotes correlates inversely with their optimal growth temperatures
Amit N. Khachane, Kenneth N. Timmis, and Vítor A. P. Martins dos Santos
Nucleic Acids Res. 2005; 33: 4016-4022. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
A sequence sub-sampling algorithm increases the power to detect distant homologues
Catrióna R. Johnston and Denis C. Shields
Nucleic Acids Res. 2005; 33: 3772-3778. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries
Michael J. Volles and Peter T. Lansbury, Jr
Nucleic Acids Res. 2005; 33: 3667-3677. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae
John Gladitz, Kai Shen, Patricia Antalis, Fen Ze Hu, J. Christopher Post, and Garth D. Ehrlich
Nucleic Acids Res. 2005; 33: 3644-3658. [Abstract] [Full text] [Print PDF]  

Articles
Human microRNA prediction through a probabilistic co-learning model of sequence and structure
Jin-Wu Nam, Ki-Roo Shin, Jinju Han, Yoontae Lee, V. Narry Kim, and Byoung-Tak Zhang
Nucleic Acids Res. 2005; 33: 3570-3581. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Identification of novel restriction endonuclease-like fold families among hypothetical proteins
Lisa N. Kinch, Krzysztof Ginalski, Leszek Rychlewski, and Nick V. Grishin
Nucleic Acids Res. 2005; 33: 3598-3605. [Abstract] [Full text] [Print PDF]  

Articles
Identification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation
Jiang Qian, Noriko Esumi, Yangjian Chen, Qingliang Wang, Itay Chowers, and Donald J. Zack
Nucleic Acids Res. 2005; 33: 3479-3491. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data
Thomas S. Price, Regina Regan, Richard Mott, Åsa Hedman, Ben Honey, Rachael J. Daniels, Lee Smith, Andy Greenfield, Ana Tiganescu, Veronica Buckle, Nicki Ventress, Helena Ayyub, Anita Salhan, Susana Pedraza-Diaz, John Broxholme, Jiannis Ragoussis, Douglas R. Higgs, Jonathan Flint, and Samantha J. L. Knight
Nucleic Acids Res. 2005; 33: 3455-3464. [Abstract] [Full text] [Print PDF]  

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