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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 221-230 of 359 total displayed.

Past content

Articles
Transcribed processed pseudogenes in the human genome: an intermediate form of expressed retrosequence lacking protein-coding ability
Paul M. Harrison, Deyou Zheng, Zhaolei Zhang, Nicholas Carriero, and Mark Gerstein
Nucleic Acids Res. 2005; 33: 2374-2383. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
TM-align: a protein structure alignment algorithm based on the TM-score
Yang Zhang and Jeffrey Skolnick
Nucleic Acids Res. 2005; 33: 2302-2309. [Abstract] [Full text] [Print PDF]  

Articles
Computational technique for improvement of the position-weight matrices for the DNA/protein binding sites
Naum I. Gershenzon, Gary D. Stormo, and Ilya P. Ioshikhes
Nucleic Acids Res. 2005; 33: 2290-2301. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Detecting DNA-binding helix–turn–helix structural motifs using sequence and structure information
Marialuisa Pellegrini-Calace and Janet M. Thornton
Nucleic Acids Res. 2005; 33: 2129-2140. [Abstract] [Full text] [Print PDF]  

Articles
Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes
Robert Castelo, Alexandre Reymond, Carine Wyss, Francisco Câmara, Genís Parra, Stylianos E. Antonarakis, Roderic Guigó, and Eduardo Eyras
Nucleic Acids Res. 2005; 33: 1935-1939. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
A computational study of off-target effects of RNA interference
Shibin Qiu, Coen M. Adema, and Terran Lane
Nucleic Acids Res. 2005; 33: 1834-1847. [Abstract] [Full text] [Print PDF]  

Articles
Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms
Suganthi Balasubramanian, Yu Xia, Elizaveta Freinkman, and Mark Gerstein
Nucleic Acids Res. 2005; 33: 1710-1721. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Integration of text- and data-mining using ontologies successfully selects disease gene candidates
Nicki Tiffin, Janet F. Kelso, Alan R. Powell, Hong Pan, Vladimir B. Bajic, and Winston A. Hide
Nucleic Acids Res. 2005; 33: 1544-1552. [Abstract] [Full text] [Print PDF]  

Articles
NestedMICA: sensitive inference of over-represented motifs in nucleic acid sequence
Thomas A. Down and Tim J. P. Hubbard
Nucleic Acids Res. 2005; 33: 1445-1453. [Abstract] [Full text] [Print PDF]  

Articles
Human pol II promoter prediction: time series descriptors and machine learning
Rajeev Gangal and Pankaj Sharma
Nucleic Acids Res. 2005; 33: 1332-1336. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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