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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 241-250 of 359 total displayed.

Past content

Articles
A statistical analysis of RNA folding algorithms through thermodynamic parameter perturbation
D. M. Layton and R. Bundschuh
Nucleic Acids Res. 2005; 33: 519-524. [Abstract] [Full text] [Print PDF]  

Methods Online
A simple method for predicting the functional differentiation of duplicate genes and its application to MIKC-type MADS-box genes
Jongmin Nam, Kerstin Kaufmann, Günter Theißen, and Masatoshi Nei
Nucleic Acids Res. 2005; 33: e12. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays
Yee Leng Yap, Maria P. Wong, Xue Wu Zhang, David Hernandez, Robin Gras, David K. Smith, and Antoine Danchin
Nucleic Acids Res. 2005; 33: 409-421. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes
Gábor E. Tusnády, István Simon, András Váradi, and Tamás Arányi
Nucleic Acids Res. 2005; 33: e9. [Abstract] [Full text] [Print PDF]  

Methods Online
Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data
Keith Le, Katherine Mitsouras, Meenakshi Roy, Qi Wang, Qiang Xu, Stanley F. Nelson, and Christopher Lee
Nucleic Acids Res. 2004; 32: e180. [Abstract] [Full text] [Print PDF] [ Supplementary Material ] [ Supplementary Material ]  

Articles
Global protein function annotation through mining genome-scale data in yeast Saccharomyces cerevisiae
Yu Chen and Dong Xu
Nucleic Acids Res. 2004; 32: 6414-6424. [Abstract] [Full text] [Print PDF]  

Articles
Predicting oligonucleotide-directed mutagenesis failures in protein engineering
Christopher D. Wassman, Phillip Y. Tam, Richard H. Lathrop, and Gregory A. Weiss
Nucleic Acids Res. 2004; 32: 6407-6413. [Abstract] [Full text] [Print PDF]  

Articles
EFICAz: a comprehensive approach for accurate genome-scale enzyme function inference
Weidong Tian, Adrian K. Arakaki, and Jeffrey Skolnick
Nucleic Acids Res. 2004; 32: 6226-6239. [Abstract] [Full text] [Print PDF] [ Supplementary Material ] [ Supplementary Material ]  

Articles
Computational method for discovery of estrogen responsive genes
Suisheng Tang, Sin Lam Tan, Suresh Kumar Ramadoss, Arun Prashanth Kumar, Man-Hung Eric Tang, and Vladimir B. Bajic
Nucleic Acids Res. 2004; 32: 6212-6217. [Abstract] [Full text] [Print PDF] [ Supplementary Material ] [ Supplementary Material ] [ Supplementary Material ]  

Articles
Novel algorithm for automated genotyping of microsatellites
Toshiko Matsumoto, Wataru Yukawa, Yasuyuki Nozaki, Ryo Nakashige, Minori Shinya, Satoshi Makino, Masaru Yagura, Tomoki Ikuta, Tadashi Imanishi, Hidetoshi Inoko, Gen Tamiya, and Takashi Gojobori
Nucleic Acids Res. 2004; 32: 6069-6077. [Abstract] [Full text] [Print PDF]  

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