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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 251-260 of 359 total displayed.

Past content

Methods Online
Hypervariable genes—experimental error or hidden dynamics
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Alan Shields, Parima Pathipvanich, James N. Jarvis, and Michael Centola
Nucleic Acids Res. 2004; 32: e147. [Abstract] [Full text] [Print PDF]  

Articles
Conservation of adjacency as evidence of paralogous operons
Sarath Chandra Janga and Gabriel Moreno-Hagelsieb
Nucleic Acids Res. 2004; 32: 5392-5397. [Abstract] [Full text] [Print PDF]  

Articles
PhyloGenie: automated phylome generation and analysis
Tancred Frickey and Andrei N. Lupas
Nucleic Acids Res. 2004; 32: 5231-5238. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
HYPROSP: a hybrid protein secondary structure prediction algorithm—a knowledge-based approach
Kuen-Pin Wu, Hsin-Nan Lin, Jia-Ming Chang, Ting-Yi Sung, and Wen-Lian Hsu
Nucleic Acids Res. 2004; 32: 5059-5065. [Abstract] [Full text] [Print PDF]  

Articles
Bipartite pattern discovery by entropy minimization-based multiple local alignment
Chengpeng Bi and Peter K. Rogan
Nucleic Acids Res. 2004; 32: 4979-4991. [Abstract] [Full text] [Print PDF]  

Articles
Predicting genes expressed via –1 and +1 frameshifts
Sanghoon Moon, Yanga Byun, Hong-Jin Kim, Sunjoo Jeong, and Kyungsook Han
Nucleic Acids Res. 2004; 32: 4884-4892. [Abstract] [Full text] [Print PDF]  

Articles
Identifying DNA-binding proteins using structural motifs and the electrostatic potential
Hugh P. Shanahan, Mario A. Garcia, Susan Jones, and Janet M. Thornton
Nucleic Acids Res. 2004; 32: 4732-4741. [Abstract] [Full text] [Print PDF]  

Articles
Rational design of DNA sequences for nanotechnology, microarrays and molecular computers using Eulerian graphs
Petr Pancoska, Zdenek Moravek, and Ute M. Moll
Nucleic Acids Res. 2004; 32: 4630-4645. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences
Y. V. Sun, D. R. Boverhof, L. D. Burgoon, M. R. Fielden, and T. R. Zacharewski
Nucleic Acids Res. 2004; 32: 4512-4523. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Transposon Express, a software application to report the identity of insertions obtained by comprehensive transposon mutagenesis of sequenced genomes: analysis of the preference for in vitro Tn5 transposition into GC-rich DNA
Paul R. Herron, Gareth Hughes, Govind Chandra, Susan Fielding, and Paul J. Dyson
Nucleic Acids Res. 2004; 32: e113. [Abstract] [Full text] [Print PDF]  

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