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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 271-280 of 359 total displayed.

Past content

Articles
Frequency of gaps observed in a structurally aligned protein pair database suggests a simple gap penalty function
Nalin C. W. Goonesekere and Byungkook Lee
Nucleic Acids Res. 2004; 32: 2838-2843. [Abstract] [Full text] [Print PDF]  

Articles
Gene mining: a novel and powerful ensemble decision approach to hunting for disease genes using microarray expression profiling
Xia Li, Shaoqi Rao, Yadong Wang, and Binsheng Gong
Nucleic Acids Res. 2004; 32: 2685-2694. [Abstract] [Full text] [Print PDF]  

Articles
Predicting transmembrane beta-barrels in proteomes
Henry R. Bigelow, Donald S. Petrey, Jinfeng Liu, Dariusz Przybylski, and Burkhard Rost
Nucleic Acids Res. 2004; 32: 2566-2577. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
A Fugu–Human Genome Synteny Viewer: web software for graphical display and annotation reports of synteny between Fugu genomic sequence and human genes
Mark Halling-Brown, Clare Sansom, David S. Moss, Greg Elgar, and Yvonne J. K. Edwards
Nucleic Acids Res. 2004; 32: 2618-2622. [Abstract] [Full text] [Print PDF]  

Articles
Contact-based sequence alignment
Jens Kleinjung, John Romein, Kuang Lin, and Jaap Heringa
Nucleic Acids Res. 2004; 32: 2464-2473. [Abstract] [Full text] [Print PDF]  

Articles
Transcription factor binding element detection using functional clustering of mutant expression data
Gengxin Chen, Naoya Hata, and Michael Q. Zhang
Nucleic Acids Res. 2004; 32: 2362-2371. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Transcriptional organization of the Clostridium acetobutylicum genome
Carlos J. Paredes, Isidore Rigoutsos, and E. Terry Papoutsakis
Nucleic Acids Res. 2004; 32: 1973-1981. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Identifying transcriptional regulatory sites in the human genome using an integrated system
Hsien-Da Huang, Jorng-Tzong Horng, Yi-Ming Sun, Ann-Ping Tsou, and Shir-Ly Huang
Nucleic Acids Res. 2004; 32: 1948-1956. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
MUSCLE: multiple sequence alignment with high accuracy and high throughput
Robert C. Edgar
Nucleic Acids Res. 2004; 32: 1792-1797. [Abstract] [Full text] [Print PDF]  

Articles
Calculating the statistical significance of physical clusters of co-regulated genes in the genome: the role of chromatin in domain-wide gene regulation
Cheng-Fu Chang, Ka-Man Wai, and Hugh G. Patterton
Nucleic Acids Res. 2004; 32: 1798-1807. [Abstract] [Full text] [Print PDF]  

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