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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 51-60 of 359 total displayed.

Past content

Methods Online
Finding 3D motifs in ribosomal RNA structures
Alberto Apostolico, Giovanni Ciriello, Concettina Guerra, Christine E. Heitsch, Chiaolong Hsiao, and Loren Dean Williams
Nucleic Acids Res. 2009; 37: e29. [Abstract] [Full text] [Print PDF]  

Computational Biology
Identifying and classifying biomedical perturbations in text
Raul Rodriguez-Esteban, Phoebe M. Roberts, and Matthew E. Crawford
Nucleic Acids Res. 2009; 37: 771-777. [Abstract] [Full text] [Print PDF]  

Computational Biology
PSI-BLAST pseudocounts and the minimum description length principle
Stephen F. Altschul, E. Michael Gertz, Richa Agarwala, Alejandro A. Schäffer, and Yi-Kuo Yu
Nucleic Acids Res. 2009; 37: 815-824. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Kalign2: high-performance multiple alignment of protein and nucleotide sequences allowing external features
Timo Lassmann, Oliver Frings, and Erik L. L. Sonnhammer
Nucleic Acids Res. 2009; 37: 858-865. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Genomics
Assessing the gene space in draft genomes
Genis Parra, Keith Bradnam, Zemin Ning, Thomas Keane, and Ian Korf
Nucleic Acids Res. 2009; 37: 289-297. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Modeling genetic inheritance of copy number variations
Kai Wang, Zhen Chen, Mahlet G. Tadesse, Joseph Glessner, Struan F. A. Grant, Hakon Hakonarson, Maja Bucan, and Mingyao Li
Nucleic Acids Res. 2008; 36: e138. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Evolutionary computation for discovery of composite transcription factor binding sites
Gary B. Fogel, V. William Porto, Gabor Varga, Ernst R. Dow, Andrew M. Craven, David M. Powers, Harry B. Harlow, Eric W. Su, Jude E. Onyia, and Chen Su
Nucleic Acids Res. 2008; 36: e142. [Abstract] [Full text] [Print PDF]  

Methods Online
Gene expression module-based chemical function similarity search
Yun Li, Pei Hao, Siyuan Zheng, Kang Tu, Haiwei Fan, Ruixin Zhu, Guohui Ding, Changzheng Dong, Chuan Wang, Xuan Li, H.-J. Thiesen, Y. Eugene Chen, Hualiang Jiang, Lei Liu, and Yixue Li
Nucleic Acids Res. 2008; 36: e137. [Abstract] [Full text] [Print PDF]  

Computational Biology
Predicting transcription factor specificity with all-atom models
Sahand Jamal Rahi, Peter Virnau, Leonid A. Mirny, and Mehran Kardar
Nucleic Acids Res. 2008; 36: 6209-6217. [Abstract] [Full text] [Print PDF]  

Computational Biology
Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments
Stefan E. Seemann, Jan Gorodkin, and Rolf Backofen
Nucleic Acids Res. 2008; 36: 6355-6362. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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