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Computational methods


Computational Methods include useful new routines and algorithms with applications to Bioinformatics such as new sequence manipulation and analysis methods. Also included are new methods of computational analysis of biological data that facilitate data interpretation.


Citations 61-70 of 359 total displayed.

Past content

Methods Online
Prioritization of candidate cancer genes—an aid to oncogenomic studies
Simon J. Furney, Borja Calvo, Pedro Larrañaga, Jose A. Lozano, and Nuria Lopez-Bigas
Nucleic Acids Res. 2008; 36: e115. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
The whole alignment and nothing but the alignment: the problem of spurious alignment flanks
Martin C. Frith, Yonil Park, Sergey L. Sheetlin, and John L. Spouge
Nucleic Acids Res. 2008; 36: 5863-5871. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
KnotInFrame: prediction of –1 ribosomal frameshift events
Corinna Theis, Jens Reeder, and Robert Giegerich
Nucleic Acids Res. 2008; 36: 6013-6020. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Functional studies on transfected cell microarray analysed by linear regression modelling
Christina Sæten Fjeldbo, Kristine Misund, Clara-Cecilie Günther, Mette Langaas, Tonje Strømmen Steigedal, Liv Thommesen, Astrid Lægreid, and Torunn Bruland
Nucleic Acids Res. 2008; 36: e97. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
End-joining long nucleic acid polymers
M. van den Hout, S. Hage, C. Dekker, and N. H. Dekker
Nucleic Acids Res. 2008; 36: e104. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
A protein–DNA docking benchmark
Marc van Dijk and Alexandre M. J. J. Bonvin
Nucleic Acids Res. 2008; 36: e88. [Abstract] [Full text] [Print PDF]  

Methods Online
Multiple segmental and selective isotope labeling of large RNA for NMR structural studies
Frank H. T. Nelissen, Adriaan J. van Gammeren, Marco Tessari, Frederic C. Girard, Hans A. Heus, and Sybren S. Wijmenga
Nucleic Acids Res. 2008; 36: e89. [Abstract] [Full text] [Print PDF]  

Computational Biology
MOPAT: a graph-based method to predict recurrent cis-regulatory modules from known motifs
Jianfei Hu, Haiyan Hu, and Xiaoman Li
Nucleic Acids Res. 2008; 36: 4488-4497. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Hit selection with false discovery rate control in genome-scale RNAi screens
Xiaohua Douglas Zhang, Pei Fen Kuan, Marc Ferrer, Xiaohua Shu, Yingxue C. Liu, Adam T. Gates, Priya Kunapuli, Erica M. Stec, Min Xu, Shane D. Marine, Daniel J. Holder, Berta Strulovici, Joseph F. Heyse, and Amy S. Espeseth
Nucleic Acids Res. 2008; 36: 4667-4679. [Abstract] [Full text] [Print PDF]  

Methods Online
Improved assay-dependent searching of nucleic acid sequence databases
Jason D. Gans and Murray Wolinsky
Nucleic Acids Res. 2008; 36: e74. [Abstract] [Full text] [Print PDF]  

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