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DNA characterisation


This category includes all new methods, or highly significant improvement thereof, for the biochemical and physical characterization of DNA. This includes DNA purification from various sources (e.g. ancient DNA, DNA from widely used hosts), DNA quantification, DNA analysis (by enzymatic, gel electrophoresis, mass-spectrometry, hybridization, assay) as well as determination of DNA sequences.


Citations 1-10 of 178 total displayed.

Most recent content

Methods Online
Separation of 1–23-kb complementary DNA strands by urea–agarose gel electrophoresis
Éva Hegedüs, Endre Kókai, Alexander Kotlyar, Viktor Dombrádi, and Gábor Szabó
Nucleic Acids Res. 2009; 37: e112. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Methods Online
Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol
Francesca Malentacchi, Giulia Forni, Serena Vinci, and Claudio Orlando
Nucleic Acids Res. 2009; 37: e86. [Abstract] [Full text] [Print PDF]  

Methods Online
Flow cytometry for enrichment and titration in massively parallel DNA sequencing
Julia Sandberg, Patrik L. Ståhl, Afshin Ahmadian, Magnus K. Bjursell, and Joakim Lundeberg
Nucleic Acids Res. 2009; 37: e63. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan
M. C. Díaz de la Loza and R. E. Wellinger
Nucleic Acids Res. 2009; 37: e26. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Sequencing by Cyclic Ligation and Cleavage (CycLiC) directly on a microarray captured template
Kalim U. Mir, Hong Qi, Oleg Salata, and Giuseppe Scozzafava
Nucleic Acids Res. 2009; 37: e5. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Tentacle probe sandwich assay in porous polymer monolith improves specificity, sensitivity and kinetics
Brent C. Satterfield, Michael R. Caplan, and Jay A. A. West
Nucleic Acids Res. 2008; 36: e129. [Abstract] [Full text] [Print PDF]  

Methods Online
Mix and measure fluorescence screening for selective quadruplex binders
Sattanathan Paramasivan and Philip H. Bolton
Nucleic Acids Res. 2008; 36: e106. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Electrical detection of the temperature induced melting transition of a DNA hairpin covalently attached to gold interdigitated microelectrodes
Greg P. Brewood, Yaswanth Rangineni, Daniel J. Fish, Ashwini S. Bhandiwad, David R. Evans, Raj Solanki, and Albert S. Benight
Nucleic Acids Res. 2008; 36: e98. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Substantial biases in ultra-short read data sets from high-throughput DNA sequencing
Juliane C. Dohm, Claudio Lottaz, Tatiana Borodina, and Heinz Himmelbauer
Nucleic Acids Res. 2008; 36: e105. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
Christoph Bock, Jörn Walter, Martina Paulsen, and Thomas Lengauer
Nucleic Acids Res. 2008; 36: e55. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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