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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 1-10 of 195 total displayed.

Most recent content

Methods Online
Exalign: a new method for comparative analysis of exon–intron gene structures
Giulio Pavesi, Federico Zambelli, Corrado Caggese, and Graziano Pesole
Nucleic Acids Res. 2008; 36: e47. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
A space-efficient and accurate method for mapping and aligning cDNA sequences onto genomic sequence
Osamu Gotoh
Nucleic Acids Res. 2008; 36: 2630-2638. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Methods Online
Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification
Harm van Bakel, Folkert J. van Werven, Marijana Radonjic, Mariel O. Brok, Dik van Leenen, Frank C. P. Holstege, and H. T. Marc Timmers
Nucleic Acids Res. 2008; 36: e21. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Detection of a circadian enhancer in the mDbp promoter using prokaryotic transposon vector-based strategy
Yota B. Kiyohara, Keigo Nishii, Maki Ukai-Tadenuma, Hiroki R. Ueda, Yasuo Uchiyama, and Kazuhiro Yagita
Nucleic Acids Res. 2008; 36: e23. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
The use of multiple displacement amplification to amplify complex DNA libraries
Melissa J. Fullwood, Jack J. S. Tan, Patrick W. P. Ng, Kuo Ping Chiu, Jun Liu, Chia Lin Wei, and Yijun Ruan
Nucleic Acids Res. 2008; 36: e32. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Performance comparison between k-tuple distance and four model-based distances in phylogenetic tree reconstruction
Kuan Yang and Liqing Zhang
Nucleic Acids Res. 2008; 36: e33. [Abstract] [Full text] [Print PDF]  

Methods Online
Bisulfite sequencing Data Presentation and Compilation (BDPC) web server—a useful tool for DNA methylation analysis
Christian Rohde, Yingying Zhang, Tomasz P. Jurkowski, Heinrich Stamerjohanns, Richard Reinhardt, and Albert Jeltsch
Nucleic Acids Res. 2008; 36: e34. [Abstract] [Full text] [Print PDF]  

Methods Online
µChIP—a rapid micro chromatin immunoprecipitation assay for small cell samples and biopsies
John Arne Dahl and Philippe Collas
Nucleic Acids Res. 2008; 36: e15. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing
Matthias Meyer, Adrian W. Briggs, Tomislav Maricic, Barbara Höber, Barbara Höffner, Johannes Krause, Antje Weihmann, Svante Pääbo, and Michael Hofreiter
Nucleic Acids Res. 2008; 36: e5. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage {phi}BT1
Zhengyao Xu, Nicholas C. O. Lee, Felix Dafhnis-Calas, Sunir Malla, Margaret C. M. Smith, and William R. A. Brown
Nucleic Acids Res. 2008; 36: e9. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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