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Genomics
This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.
Citations 1-10 of 258 total displayed.
- Methods Online
A high throughput experimental approach to identify miRNA targets in human cells
- Lu Ping Tan, Erwin Seinen, Gerben Duns, Debora de Jong, Ody C. M. Sibon, Sibrand Poppema, Bart-Jan Kroesen, Klaas Kok, and Anke van den Berg
Nucleic Acids Res. 2009; 37: e137.
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- Methods Online
High-throughput detection and multiplex identification of cell contaminations
- Markus Schmitt and Michael Pawlita
Nucleic Acids Res. 2009; 37: e119.
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- Methods Online
An efficient method to assemble linear DNA templates for in vitro screening and selection systems
- Viktor Stein and Florian Hollfelder
Nucleic Acids Res. 2009; 37: e122.
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- Methods Online
Transcriptome analysis by strand-specific sequencing of complementary DNA
- Dmitri Parkhomchuk, Tatiana Borodina, Vyacheslav Amstislavskiy, Maria Banaru, Linda Hallen, Sylvia Krobitsch, Hans Lehrach, and Alexey Soldatov
Nucleic Acids Res. 2009; 37: e123.
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- Methods Online
SubpathwayMiner: a software package for flexible identification of pathways
- Chunquan Li, Xia Li, Yingbo Miao, Qianghu Wang, Wei Jiang, Chun Xu, Jing Li, Junwei Han, Fan Zhang, Binsheng Gong, and Liangde Xu
Nucleic Acids Res. 2009; 37: e131.
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- Computational Biology
Detecting species-site dependencies in large multiple sequence alignments
- Roland Schwarz, Philipp N. Seibel, Sven Rahmann, Christoph Schoen, Mirja Huenerberg, Clemens Müller-Reible, Thomas Dandekar, Rachel Karchin, Jörg Schultz, and Tobias Müller
Nucleic Acids Res. 2009; 37: 5959-5968.
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- Methods Online
Detection of single nucleotide variations in expressed exons of the human genome using RNA-Seq
- Iouri Chepelev, Gang Wei, Qingsong Tang, and Keji Zhao
Nucleic Acids Res. 2009; 37: e106.
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- Methods Online
A genome-wide library of CB4856/N2 introgression lines of Caenorhabditis elegans
- Agnieszka Doroszuk, L. Basten Snoek, Emilie Fradin, Joost Riksen, and Jan Kammenga
Nucleic Acids Res. 2009; 37: e110.
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- Methods Online
Studying human telomerase gene transcription by a chromatinized reporter generated by recombinase-mediated targeting of a bacterial artificial chromosome
- Shuwen Wang, Yuanjun Zhao, Melanie A. Leiby, and Jiyue Zhu
Nucleic Acids Res. 2009; 37: e111.
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- Methods Online
Separation of 1–23-kb complementary DNA strands by urea–agarose gel electrophoresis
- Éva Hegedüs, Endre Kókai, Alexander Kotlyar, Viktor Dombrádi, and Gábor Szabó
Nucleic Acids Res. 2009; 37: e112.
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