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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 91-100 of 258 total displayed.

Past content

Computational Biology
Automated recognition of retroviral sequences in genomic data—RetroTector©
Göran O. Sperber, Tove Airola, Patric Jern, and Jonas Blomberg
Nucleic Acids Res. 2007; 35: 4964-4976. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Computational Biology
Dissecting the action of an evolutionary conserved non-coding region on renin promoter activity
Ralf Mrowka, Andreas Steege, Charlotte Kaps, Hanspeter Herzel, Bernd J. Thiele, Pontus B. Persson, and Nils Blüthgen
Nucleic Acids Res. 2007; 35: 5120-5129. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Generation of an inducible and optimized piggyBac transposon system
Juan Cadiñanos and Allan Bradley
Nucleic Acids Res. 2007; 35: e87. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference
Christiane Hitz, Wolfgang Wurst, and Ralf Kühn
Nucleic Acids Res. 2007; 35: e90. [Abstract] [Full text] [Print PDF]  

Methods Online
An adaptation of the LMS method to determine expression variations in profiling data
Paul Chuchana, Dorian Marchand, Mélanie Nugoli, Carmen Rodriguez, Nicolas Molinari, and Jose A. Garcia-Sanz
Nucleic Acids Res. 2007; 35: e71. [Abstract] [Full text] [Print PDF]  

Computational Biology
RNAmmer: consistent and rapid annotation of ribosomal RNA genes
Karin Lagesen, Peter Hallin, Einar Andreas Rødland, Hans-Henrik Stærfeldt, Torbjørn Rognes, and David W. Ussery
Nucleic Acids Res. 2007; 35: 3100-3108. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Real-time PCR mapping of DNaseI-hypersensitive sites using a novel ligation-mediated amplification technique
George A. Follows, Mary E. Janes, Ludovic Vallier, Anthony R. Green, and Berthold Gottgens
Nucleic Acids Res. 2007; 35: e56. [Abstract] [Full text] [Print PDF]  

Methods Online
A recombineering based approach for high-throughput conditional knockout targeting vector construction
Waiin Chan, Nina Costantino, Ruixue Li, Song Choon Lee, Qin Su, David Melvin, Donald L. Court, and Pentao Liu
Nucleic Acids Res. 2007; 35: e64. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Computational Biology
Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations
Steven Van Vooren, Bernard Thienpont, Björn Menten, Frank Speleman, Bart De Moor, Joris Vermeesch, and Yves Moreau
Nucleic Acids Res. 2007; 35: 2533-2543. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma
Stefan Pfister, Christof Schlaeger, Frank Mendrzyk, Andrea Wittmann, Axel Benner, Andreas Kulozik, Wolfram Scheurlen, Bernhard Radlwimmer, and Peter Lichter
Nucleic Acids Res. 2007; 35: e51. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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