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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 141-150 of 258 total displayed.

Past content

Articles
Genomic scale sub-family assignment of protein domains
Julian Gough
Nucleic Acids Res. 2006; 34: 3625-3633. [Abstract] [Full text] [Print PDF]  

Methods Online
Chromosome-wide identification of novel imprinted genes using microarrays and uniparental disomies
Reiner Schulz, Trevelyan R. Menheniott, Kathryn Woodfine, Andrew J. Wood, Jonathan D. Choi, and Rebecca J. Oakey
Nucleic Acids Res. 2006; 34: e88. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Multiplex sequencing of paired-end ditags (MS-PET): a strategy for the ultra-high-throughput analysis of transcriptomes and genomes
Patrick Ng, Jack J.S. Tan, Hong Sain Ooi, Yen Ling Lee, Kuo Ping Chiu, Melissa J. Fullwood, Kandhadayar G. Srinivasan, Clotilde Perbost, Lei Du, Wing-Kin Sung, Chia-Lin Wei, and Yijun Ruan
Nucleic Acids Res. 2006; 34: e84. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Sequence biases in large scale gene expression profiling data
Asim S. Siddiqui, Allen D. Delaney, Angelique Schnerch, Obi L. Griffith, Steven J. M. Jones, and Marco A. Marra
Nucleic Acids Res. 2006; 34: e83. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Genomic DNA functions as a universal external standard in quantitative real-time PCR
James J. Yun, Lawrence E. Heisler, Irene I. L. Hwang, Olivia Wilkins, Suzanne K. Lau, Martin Hyrcza, Bamini Jayabalasingham, Jing Jin, JoAnne McLaurin, Ming-Sound Tsao, and Sandy D. Der
Nucleic Acids Res. 2006; 34: e85. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR
Claudia Gebhard, Lucia Schwarzfischer, Thu Hang Pham, Reinhard Andreesen, Andreas Mackensen, and Michael Rehli
Nucleic Acids Res. 2006; 34: e82. [Abstract] [Full text] [Print PDF]  

Methods Online
Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing
Richard J. Shaw, Emily K. Akufo-Tetteh, Janet M. Risk, John K. Field, and Triantafillos Liloglou
Nucleic Acids Res. 2006; 34: e78. [Abstract] [Full text] [Print PDF]  

Articles
Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria
Ze-Chun Yuan, Rahat Zaheer, Richard Morton, and Turlough M. Finan
Nucleic Acids Res. 2006; 34: 2686-2697. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Single-cell chromosomal imbalances detection by array CGH
Cedric Le Caignec, Claudia Spits, Karen Sermon, Martine De Rycke, Bernard Thienpont, Sophie Debrock, Catherine Staessen, Yves Moreau, Jean-Pierre Fryns, Andre Van Steirteghem, Inge Liebaers, and Joris R. Vermeesch
Nucleic Acids Res. 2006; 34: e68. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
GREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeats
Anton Buzdin, Elena Kovalskaya-Alexandrova, Elena Gogvadze, and Eugene Sverdlov
Nucleic Acids Res. 2006; 34: e67. [Abstract] [Full text] [Print PDF]  

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