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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 171-180 of 258 total displayed.

Past content

Articles
Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays
Joydeep Basu, Gregory Stromberg, George Compitello, Huntington F. Willard, and Gil Van Bokkelen
Nucleic Acids Res. 2005; 33: 587-596. [Abstract] [Full text] [Print PDF]  

Methods Online
Covalent antibody display—an in vitro antibody-DNA library selection system
Herald Reiersen, Inger Løbersli, Geir Å. Løset, Else Hvattum, Bjørg Simonsen, John E. Stacy, Duncan McGregor, Kevin FitzGerald, Martin Welschof, Ole H. Brekke, and Ole J. Marvik
Nucleic Acids Res. 2005; 33: e10. [Abstract] [Full text] [Print PDF]  

Methods Online
Detection and characterization of horizontal transfers in prokaryotes using genomic signature
Christine Dufraigne, Bernard Fertil, Sylvain Lespinats, Alain Giron, and Patrick Deschavanne
Nucleic Acids Res. 2005; 33: e6. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
ArrayOme: a program for estimating the sizes of microarray-visualized bacterial genomes
Hong-Yu Ou, Rebecca Smith, Sacha Lucchini, Jay Hinton, Roy R. Chaudhuri, Mark Pallen, Michael R. Barer, and Kumar Rajakumar
Nucleic Acids Res. 2005; 33: e3. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Identification of genes with fast-evolving regions in microbial genomes
Yu Zheng, Richard J. Roberts, and Simon Kasif
Nucleic Acids Res. 2004; 32: 6347-6357. [Abstract] [Full text] [Print PDF] [ Supplementary Material ] [ Supplementary Material ] [ Supplementary Material ]  

Methods Online
Genomewide linkage searches for Mendelian disease loci can be efficiently conducted using high-density SNP genotyping arrays
Gabrielle S. Sellick, Cheryl Longman, John Tolmie, Ruth Newbury-Ecob, Lynn Geenhalgh, Simon Hughes, Margo Whiteford, Christine Garrett, and Richard S. Houlston
Nucleic Acids Res. 2004; 32: e164. [Abstract] [Full text] [Print PDF]  

Methods Online
Bigenic Cre/loxP, pu{Delta}tk conditional genetic ablation
You-Tzung Chen, Regis Levasseur, Sukeshi Vaishnav, Gerard Karsenty, and Allan Bradley
Nucleic Acids Res. 2004; 32: e161. [Abstract] [Full text] [Print PDF]  

Methods Online
Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH
Joana Cardoso, Lia Molenaar, Renée X. de Menezes, Carla Rosenberg, Hans Morreau, Gabriela Möslein, Riccardo Fodde, and Judith M. Boer
Nucleic Acids Res. 2004; 32: e146. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Multiplex PCR/liquid chromatography assay for detection of gene rearrangements: application to RB1 gene
C. Dehainault, A. Laugé, V. Caux-Moncoutier, S. Pagès-Berhouet, F. Doz, L. Desjardins, J. Couturier, M. Gauthier-Villars, D. Stoppa-Lyonnet, and C. Houdayer
Nucleic Acids Res. 2004; 32: e139. [Abstract] [Full text] [Print PDF]  

Articles
Microfluidic PicoArray synthesis of oligodeoxynucleotides and simultaneous assembling of multiple DNA sequences
Xiaochuan Zhou, Shiying Cai, Ailing Hong, Qimin You, Peilin Yu, Nijing Sheng, Onnop Srivannavit, Seema Muranjan, Jean Marie Rouillard, Yongmei Xia, Xiaolin Zhang, Qin Xiang, Renuka Ganesh, Qi Zhu, Anna Matejko, Erdogan Gulari, and Xiaolian Gao
Nucleic Acids Res. 2004; 32: 5409-5417. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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