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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 181-190 of 258 total displayed.

Past content

Methods Online
Rapid tagging of endogenous mouse genes by recombineering and ES cell complementation of tetraploid blastocysts
Dewang Zhou, Jin-Xiang Ren, Thomas M. Ryan, N. Patrick Higgins, and Tim M. Townes
Nucleic Acids Res. 2004; 32: e128. [Abstract] [Full text] [Print PDF]  

Methods Online
Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments
Torstein Tengs, Thomas LaFramboise, Robert B. Den, David N. Hayes, Jianhua Zhang, Saikat DebRoy, Robert C. Gentleman, Keith O'Neill, Bruce Birren, and Matthew Meyerson
Nucleic Acids Res. 2004; 32: e121. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
An in vitro strategy for the selective isolation of anomalous DNA from prokaryotic genomes
M. W. J. van Passel, A. Bart, R. J. A. Waaijer, A. C. M. Luyf, A. H. C. van Kampen, and A. van der Ende
Nucleic Acids Res. 2004; 32: e114. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Detecting single DNA copy number variations in complex genomes using one nanogram of starting DNA and BAC-array CGH
Marine Guillaud-Bataille, Alexander Valent, Pascal Soularue, Christine Perot, Maria-del-Mar Inda, Aline Receveur, Sadek Smaïli, Hugues Roest Crollius, Jean Bénard, Alain Bernheim, Xavier Gidrol, and Gisèle Danglot
Nucleic Acids Res. 2004; 32: e112. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples
Gang Wang, Cameron Brennan, Martha Rook, Jia Liu Wolfe, Christopher Leo, Lynda Chin, Hongjie Pan, Wei-Hua Liu, Brendan Price, and G. Mike Makrigiorgos
Nucleic Acids Res. 2004; 32: e76. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Genome coverage and sequence fidelity of {phi}29 polymerase-based multiple strand displacement whole genome amplification
J. Guillermo Paez, Ming Lin, Rameen Beroukhim, Jeffrey C. Lee, Xiaojun Zhao, Daniel J. Richter, Stacey Gabriel, Paula Herman, Hidefumi Sasaki, David Altshuler, Cheng Li, Matthew Meyerson, and William R. Sellers
Nucleic Acids Res. 2004; 32: e71. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA
Kwong-Kwok Wong, Yvonne T. M. Tsang, Jianhe Shen, Rita S. Cheng, Yi-Mieng Chang, Tsz-Kwong Man, and Ching C. Lau
Nucleic Acids Res. 2004; 32: e69. [Abstract] [Full text] [Print PDF]  

Articles
Quantitative oligonucleotide microarray fingerprinting of Salmonella enterica isolates
Alan Willse, Timothy M. Straub, Sharon C. Wunschel, Jack A. Small, Douglas R. Call, Don S. Daly, and Darrell P. Chandler
Nucleic Acids Res. 2004; 32: 1848-1856. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Improving the sensitivity and specificity of gene expression analysis in highly related organisms through the use of electronic masks
Shailender Nagpal, Mazen W. Karaman, Michelle M. Timmerman, Vincent V. Ho, Brian L. Pike, and Joseph G. Hacia
Nucleic Acids Res. 2004; 32: e51. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

NAR Methods Online
Unlocking hidden genomic sequence
Jonathan M. Keith, Duncan A. E. Cochran, Gita H. Lala, Peter Adams, Darryn Bryant, and Keith R. Mitchelson
Nucleic Acids Res. 2004; 32: e35. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

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