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Genomics
This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.
Citations 11-20 of 258 total displayed.
- Methods Online
Conserved principles of mammalian transcriptional regulation revealed by RNA half-life
- Caroline C. Friedel, Lars Dölken, Zsolt Ruzsics, Ulrich H. Koszinowski, and Ralf Zimmer
Nucleic Acids Res. 2009; 37: e115.
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- Methods Online
Integrase-directed recovery of functional genes from genomic libraries
- Dean A. Rowe-Magnus
Nucleic Acids Res. 2009; 37: e118.
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- Methods Online
Gene silencing in the marine diatom Phaeodactylum tricornutum
- Valentina De Riso, Raffaella Raniello, Florian Maumus, Alessandra Rogato, Chris Bowler, and Angela Falciatore
Nucleic Acids Res. 2009; 37: e96.
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- Methods Online
Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells
- Mark Johnson, Hui Hui Phua, Sophia C. Bennett, Jennifer M. Spence, and Christine J. Farr
Nucleic Acids Res. 2009; 37: e98.
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- Methods Online
Using reads to annotate the genome: influence of length, background distribution, and sequence errors on prediction capacity
- Nicolas Philippe, Anthony Boureux, Laurent Bréhélin, Jorma Tarhio, Thérèse Commes, and Éric Rivals
Nucleic Acids Res. 2009; 37: e104.
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- Computational Biology
Gains and unexpected lessons from genome-scale promoter mapping
- K. S. Shavkunov, I. S. Masulis, M. N. Tutukina, A. A. Deev, and O. N. Ozoline
Nucleic Acids Res. 2009; 37: 4919-4931.
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- Genomics
A computational procedure to identify significant overlap of differentially expressed and genomic imbalanced regions in cancer datasets
- Silvio Bicciato, Roberta Spinelli, Mattia Zampieri, Eleonora Mangano, Francesco Ferrari, Luca Beltrame, Ingrid Cifola, Clelia Peano, Aldo Solari, and Cristina Battaglia
Nucleic Acids Res. 2009; 37: 5057-5070.
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- Methods Online
p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication
- Engin Gürlevik, Norman Woller, Peter Schache, Nisar P. Malek, Thomas C. Wirth, Lars Zender, Michael P. Manns, Stefan Kubicka, and Florian Kühnel
Nucleic Acids Res. 2009; 37: e84.
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- Methods Online
Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol
- Francesca Malentacchi, Giulia Forni, Serena Vinci, and Claudio Orlando
Nucleic Acids Res. 2009; 37: e86.
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- Methods Online
A novel method for tissue-specific RNAi rescue in Drosophila
- Joachim G. Schulz, Guido David, and Bassem A. Hassan
Nucleic Acids Res. 2009; 37: e93.
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