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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 241-250 of 258 total displayed.

Past content

NAR Methods Online
Locus-specific contig assembly in highly-duplicated genomes, using the BAC-RF method
Yann-rong Lin, Xavier Draye, Xiaoyin Qian, Shuzin Ren, Ling-hua Zhu, Jeff Tomkins, Rod A. Wing, Zhikang Li, and Andrew H. Paterson
Nucleic Acids Res. 2000; 28: e23. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Signal-exon trap: a novel method for the identification of signal sequences from genomic DNA
Miklós Péterfy, Tibor Gyuris, and László Takács
Nucleic Acids Res. 2000; 28: e26. [Abstract] [Full text] [Print PDF]  

Articles
NotI clones in the analysis of the human genome
Eugene R. Zabarovsky, Rinat Gizatullin, Raf M. Podowski, Veronika V. Zabarovska, Li Xie, Olga V. Muravenko, Sergei Kozyrev, Lev Petrenko, Natalia Skobeleva, Jingfeng Li, Alexei Protopopov, Vladimir Kashuba, Ingemar Ernberg, Gösta Winberg, and Claes Wahlestedt
Nucleic Acids Res. 2000; 28: 1635-1639. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Cloning of polymorphisms (COP): enrichment of polymorphic sequences from complex genomes
Jingfeng Li, Fuli Wang, Veronika Zabarovska, Claes Wahlestedt, and Eugene R. Zabarovsky
Nucleic Acids Res. 2000; 28: e1. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Transcript quantitation in total yeast cellular RNA using kinetic PCR
John J. Kang, Robert M. Watson, Mary E. Fisher, Russell Higuchi, David H. Gelfand, and Michael J. Holland
Nucleic Acids Res. 2000; 28: e2. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Interspersed repetitive sequence (IRS)–PCR for typing of whole genome radiation hybrid panels
Heinz Himmelbauer, Leonard C. Schalkwyk, and Hans Lehrach
Nucleic Acids Res. 2000; 28: e7. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Identification and characterisation of novel human Y-chromosomal microsatellites from sequence database information
Qasim Ayub, Aisha Mohyuddin, Raheel Qamar, Kehkashan Mazhar, Tatiana Zerjal, S. Qasim Mehdi, and Chris Tyler-Smith
Nucleic Acids Res. 2000; 28: e8. [Abstract] [Full text] [Print PDF]  

Articles
Oligonucleotide-conjugated beads for transdominant genetic experiments
Michael J. Feldhaus, Michael Lualhati, Karen Cardon, Bruce Roth, and Alexander Kamb
Nucleic Acids Res. 2000; 28: 534-543. [Abstract] [Full text] [Print PDF]  

Articles
Measurement of locus copy number by hybridisation with amplifiable probes
John A. L. Armour, Carolina Sismani, Philippos C. Patsalis, and Gareth Cross
Nucleic Acids Res. 2000; 28: 605-609. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
In situ localized amplification and contact replication of many individual DNA molecules
RD Mitra and GM Church
Nucleic Acids Res. 1999; 27: e34. [Abstract] [Full text] [Print PDF]  

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