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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 251-258 of 258 total displayed.

Past content

NAR Methods Online
High-throughput plasmid DNA purification for 3 cents per sample
MA Marra, TA Kucaba, LW Hillier, and RH Waterston
Nucleic Acids Res. 1999; 27: e37. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Normalization of array hybridization experiments in differential gene expression analysis
B Eickhoff, B Korn, M Schick, A Poustka, and J van der Bosch
Nucleic Acids Res. 1999; 27: e33. [Abstract] [Full text] [Print PDF]  

Articles
Synthesis of polyacrylamides N-substituted with PNA-like oligonucleotide mimics for molecular diagnostic applications
VA Efimov, AA Buryakova, and OG Chakhmakhcheva
Nucleic Acids Res. 1999; 27: 4416-4426. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Detection of homozygous deletions in tumors by hybridization of representational difference analysis (RDA) products to chromosome- specific YAC clone arrays
M Zeschnigk, B Horsthemke, and D Lohmann
Nucleic Acids Res. 1999; 27: e30. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Differential subtraction chain, a method for identifying differences in genomic DNA and mRNA
JH Luo, JA Puc, ED Slosberg, Y Yao, JN Bruce, TC Wright, Jr, MJ Becich, and R Parsons
Nucleic Acids Res. 1999; 27: e24. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Use of a linear multicopy vector based on the mini-replicon of temperate coliphage N15 for cloning DNA with abnormal secondary structures
NV Ravin and VK Ravin
Nucleic Acids Res. 1999; 27: e13. [Abstract] [Full text] [Print PDF]  

Articles
A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice
B Zheng, AA Mills, and A Bradley
Nucleic Acids Res. 1999; 27: 2354-2360. [Abstract] [Full text] [Print PDF]  

Articles
Versatile derivatisation of solid support media for covalent bonding on DNA-microchips
M Beier and JD Hoheisel
Nucleic Acids Res. 1999; 27: 1970-1977. [Abstract] [Full text] [Print PDF]  

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