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Genomics
This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.
Citations 31-40 of 258 total displayed.
- Methods Online
A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU)
- Siripan Limsirichaikul, Atsuko Niimi, Heather Fawcett, Alan Lehmann, Shunichi Yamashita, and Tomoo Ogi
Nucleic Acids Res. 2009; 37: e31.
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- Methods Online
A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells
- Melanie I. Trombly, Hong Su, and Xiaozhong Wang
Nucleic Acids Res. 2009; 37: e34.
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- Methods Online
Sensitive fluorescence detection of nucleic acids based on isothermal circular strand-displacement polymerization reaction
- Qiuping Guo, Xiaohai Yang, Kemin Wang, Weihong Tan, Wei Li, Hongxing Tang, and Huimin Li
Nucleic Acids Res. 2009; 37: e20.
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- Computational Biology
Genome-wide searching with base-pairing kernel functions for noncoding RNAs: computational and expression analysis of snoRNA families in Caenorhabditis elegans
- Kensuke Morita, Yutaka Saito, Kengo Sato, Kotaro Oka, Kohji Hotta, and Yasubumi Sakakibara
Nucleic Acids Res. 2009; 37: 999-1009.
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- Methods Online
Using shotgun sequence data to find active restriction enzyme genes
- Yu Zheng, Janos Posfai, Richard D. Morgan, Tamas Vincze, and Richard J. Roberts
Nucleic Acids Res. 2009; 37: e1.
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- Methods Online
Improvement of bacterial transformation efficiency using plasmid artificial modification
- Kazumasa Yasui, Yasunobu Kano, Kaori Tanaka, Kunitomo Watanabe, Mariko Shimizu-Kadota, Hirofumi Yoshikawa, and Tohru Suzuki
Nucleic Acids Res. 2009; 37: e3.
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- Methods Online
Sequencing by Cyclic Ligation and Cleavage (CycLiC) directly on a microarray captured template
- Kalim U. Mir, Hong Qi, Oleg Salata, and Giuseppe Scozzafava
Nucleic Acids Res. 2009; 37: e5.
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- Methods Online
A single molecule array for digital targeted molecular analyses
- Jenny Göransson, Carolina Wählby, Magnus Isaksson, W. Mathias Howell, Jonas Jarvius, and Mats Nilsson
Nucleic Acids Res. 2009; 37: e7.
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- Methods Online
The application of real-time PCR to the analysis of T cell repertoires
- Peter Wettstein, Michael Strausbauch, Terry Therneau, and Nancy Borson
Nucleic Acids Res. 2008; 36: e140.
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- Methods Online
Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms
- Peter A. C. 't Hoen, Yavuz Ariyurek, Helene H. Thygesen, Erno Vreugdenhil, Rolf H. A. M. Vossen, Renée X. de Menezes, Judith M. Boer, Gert-Jan B. van Ommen, and Johan T. den Dunnen
Nucleic Acids Res. 2008; 36: e141.
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