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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 41-50 of 258 total displayed.

Past content

Methods Online
Multiplex sequencing of plant chloroplast genomes using Solexa sequencing-by-synthesis technology
Richard Cronn, Aaron Liston, Matthew Parks, David S. Gernandt, Rongkun Shen, and Todd Mockler
Nucleic Acids Res. 2008; 36: e122. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Enhanced gene trapping in mouse embryonic stem cells
Frank Schnütgen, Jens Hansen, Silke De-Zolt, Carsten Horn, Marcus Lutz, Thomas Floss, Wolfgang Wurst, Patricia Ruiz Noppinger, and Harald von Melchner
Nucleic Acids Res. 2008; 36: e133. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
A probabilistic generative model for GO enrichment analysis
Yong Lu, Roni Rosenfeld, Itamar Simon, Gerard J. Nau, and Ziv Bar-Joseph
Nucleic Acids Res. 2008; 36: e109. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
An approach of orthology detection from homologous sequences under minimum evolution
Kyung Mo Kim, Samsun Sung, Gustavo Caetano-Anollés, Jae Yong Han, and Heebal Kim
Nucleic Acids Res. 2008; 36: e110. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation
Weimin L. Kaufman, Ibrahim Kocman, Vishal Agrawal, Hans-Peter Rahn, Daniel Besser, and Manfred Gossen
Nucleic Acids Res. 2008; 36: e111. [Abstract] [Full text] [Print PDF]  

Methods Online
Analysis of copy number variation using quantitative interspecies competitive PCR
Nigel M. Williams, Hywel Williams, Elisa Majounie, Nadine Norton, Beate Glaser, Huw R. Morris, Michael J. Owen, and Michael C. O’Donovan
Nucleic Acids Res. 2008; 36: e112. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition
Jun Fu, Silke C. Wenzel, Olena Perlova, Junping Wang, Frank Gross, Zhiru Tang, Yulong Yin, A. Francis Stewart, Rolf Müller, and Youming Zhang
Nucleic Acids Res. 2008; 36: e113. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs
Julio Gómez-Rodríguez, Valance Washington, Jun Cheng, Amalia Dutra, Evgenia Pak, Pentao Liu, Daniel W. McVicar, and Pamela L. Schwartzberg
Nucleic Acids Res. 2008; 36: e117. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Functional studies on transfected cell microarray analysed by linear regression modelling
Christina Sæten Fjeldbo, Kristine Misund, Clara-Cecilie Günther, Mette Langaas, Tonje Strømmen Steigedal, Liv Thommesen, Astrid Lægreid, and Torunn Bruland
Nucleic Acids Res. 2008; 36: e97. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Genomics
A comparison of random sequence reads versus 16S rDNA sequences for estimating the biodiversity of a metagenomic library
Chaysavanh Manichanh, Charles E. Chapple, Lionel Frangeul, Karine Gloux, Roderic Guigo, and Joel Dore
Nucleic Acids Res. 2008; 36: 5180-5188. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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