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Genomics


This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.


Citations 51-60 of 258 total displayed.

Past content

Computational Biology
The cis-regulatory map of Shewanella genomes
Jiajian Liu, Xing Xu, and Gary D. Stormo
Nucleic Acids Res. 2008; 36: 5376-5390. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx)
Amy J. Baldwin, Kathy Busse, Alan M. Simm, and D. Dafydd Jones
Nucleic Acids Res. 2008; 36: e77. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Primase-based whole genome amplification
Ying Li, Hyun-Jin Kim, Chunyang Zheng, Wing Huen A. Chow, Jeonghwa Lim, Brendan Keenan, Xiaojing Pan, Bertrand Lemieux, and Huimin Kong
Nucleic Acids Res. 2008; 36: e79. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Impact of whole genome amplification on analysis of copy number variants
T. J. Pugh, A. D. Delaney, N. Farnoud, S. Flibotte, M. Griffith, H. I. Li, H. Qian, P. Farinha, R. D. Gascoyne, and M. A. Marra
Nucleic Acids Res. 2008; 36: e80. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping
Daniel J. Turner, Chris Tyler-Smith, and Matthew E. Hurles
Nucleic Acids Res. 2008; 36: e82. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Rapid and efficient construction of markerless deletions in the Escherichia coli genome
Byung Jo Yu, Kui Hyeon Kang, Jun Hyoung Lee, Bong Hyun Sung, Mi Sun Kim, and Sun Chang Kim
Nucleic Acids Res. 2008; 36: e84. [Abstract] [Full text] [Print PDF]  

Methods Online
Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays
Kaarel Krjutskov, Reidar Andreson, Reedik Mägi, Tiit Nikopensius, Andrey Khrunin, Evelin Mihailov, Veronika Tammekivi, Helena Sork, Maido Remm, and Andres Metspalu
Nucleic Acids Res. 2008; 36: e75. [Abstract] [Full text] [Print PDF]  

Genomics
Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site
Geetu Tuteja, Shane T. Jensen, Peter White, and Klaus H. Kaestner
Nucleic Acids Res. 2008; 36: 4149-4157. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Microarray-based global mapping of integration sites for the retrotransposon, intracisternal A-particle, in the mouse genome
Takashi Takabatake, Hiroshi Ishihara, Yasushi Ohmachi, Izumi Tanaka, Masako M. Nakamura, Katsuyoshi Fujikawa, Tokuhisa Hirouchi, Shizuko Kakinuma, Yoshiya Shimada, Yoichi Oghiso, and Kimio Tanaka
Nucleic Acids Res. 2008; 36: e59. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Molecular Biology
Base-pair neutral homozygotes can be discriminated by calibrated high-resolution melting of small amplicons
Cameron N. Gundry, Steven F. Dobrowolski, Y. Ranae Martin, Thomas C. Robbins, Lyle M. Nay, Nathan Boyd, Thomas Coyne, Mikeal D. Wall, Carl T. Wittwer, and David H.-F. Teng
Nucleic Acids Res. 2008; 36: 3401-3408. [Abstract] [Full text] [Print PDF]  

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