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Genomics
This category presents new strategies for the genomic scale analyses. Examples include, but are not limited to, positional or whole genome cloning (e.g. using HAC, BAC, YAC, or P1 systems, see also CLONING), mapping, large scale sequencing, synteny characterization and the global evaluation of genes and their expression patterns (see also MONITORING GENE EXPRESSION). Strategies involve traditional molecular biology methods as well as new technologies such as arrays.
Citations 81-90 of 258 total displayed.
- Methods Online
Efficacy assessment of SNP sets for genome-wide disease association studies
- Andreas Wollstein, Alexander Herrmann, Michael Wittig, Michael Nothnagel, Andre Franke, Peter Nürnberg, Stefan Schreiber, Michael Krawczak, and Jochen Hampe
Nucleic Acids Res. 2007; 35: e113.
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- Methods Online
MLGA—a rapid and cost-efficient assay for gene copy-number analysis
- Magnus Isaksson, Johan Stenberg, Fredrik Dahl, Ann-Charlotte Thuresson, Marie-Louise Bondeson, and Mats Nilsson
Nucleic Acids Res. 2007; 35: e115.
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- Methods Online
Vitamin H-regulated transgene expression in mammalian cells
- Wilfried Weber, William Bacchus, Marie Daoud-El Baba, and Martin Fussenegger
Nucleic Acids Res. 2007; 35: e116.
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- Methods Online
A UTF1-based selection system for stable homogeneously pluripotent human embryonic stem cell cultures
- Shen Mynn Tan, Siew Tein Wang, Hannes Hentze, and Peter Dröge
Nucleic Acids Res. 2007; 35: e118.
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- Methods Online
Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements
- Marcel W. Coolen, Aaron L. Statham, Margaret Gardiner-Garden, and Susan J. Clark
Nucleic Acids Res. 2007; 35: e119.
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- Methods Online
High-precision mapping of protein–protein interfaces: an integrated genetic strategy combining en masse mutagenesis and DNA-level parallel analysis on a yeast two-hybrid platform
- Maria Pajunen, Hilkka Turakainen, Eini Poussu, Johan Peränen, Mauno Vihinen, and Harri Savilahti
Nucleic Acids Res. 2007; 35: e103.
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- Methods Online
Live cell imaging of repetitive DNA sequences via GFP-tagged polydactyl zinc finger proteins
- Beatrice I. Lindhout, Paul Fransz, Federico Tessadori, Tobias Meckel, Paul J.J. Hooykaas, and Bert J. van der Zaal
Nucleic Acids Res. 2007; 35: e107.
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- Computational Biology
A survey of bacterial insertion sequences using IScan
- Andreas Wagner, Christopher Lewis, and Manuel Bichsel
Nucleic Acids Res. 2007; 35: 5284-5293.
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- Computational Biology
A systematic strategy for large-scale analysis of genotype–phenotype correlations: identification of candidate genes involved in African trypanosomiasis
- Paul Fisher, Cornelia Hedeler, Katherine Wolstencroft, Helen Hulme, Harry Noyes, Stephen Kemp, Robert Stevens, and Andrew Brass
Nucleic Acids Res. 2007; 35: 5625-5633.
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- Methods Online
Targeted high-throughput sequencing of tagged nucleic acid samples
- Matthias Meyer, Udo Stenzel, Sean Myles, Kay Prüfer, and Michael Hofreiter
Nucleic Acids Res. 2007; 35: e97.
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