Skip Navigation

Mutagenesis


This category presents widely useful methods for random or site-specific, chemical or enzymatic, in vitro or in vivo mutagenesis.


Citations 1-10 of 81 total displayed.

Most recent content

Methods Online
TrimerDimer: an oligonucleotide-based saturation mutagenesis approach that removes redundant and stop codons
Paul Gaytán, Casandra Contreras-Zambrano, Mónica Ortiz-Alvarado, Alfredo Morales-Pablos, and Jorge Yáñez
Nucleic Acids Res. 2009; 37: e125. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Molecular Biology
Targeted correction of a thalassemia-associated β-globin mutation induced by pseudo-complementary peptide nucleic acids
Pallavi Lonkar, Ki-Hyun Kim, Jean Y. Kuan, Joanna Y. Chin, Faye A. Rogers, Melissa P. Knauert, Ryszard Kole, Peter E. Nielsen, and Peter M. Glazer
Nucleic Acids Res. 2009; 37: 3635-3644. [Abstract] [Full text] [Print PDF]  

Methods Online
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization
Douglas D. Young, Hrvoje Lusic, Mark O. Lively, and Alexander Deiters
Nucleic Acids Res. 2009; 37: e58. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Mutagenic inverted repeat assisted genome engineering (MIRAGE)
Nikhil U. Nair and Huimin Zhao
Nucleic Acids Res. 2009; 37: e9. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Enhanced gene trapping in mouse embryonic stem cells
Frank Schnütgen, Jens Hansen, Silke De-Zolt, Carsten Horn, Marcus Lutz, Thomas Floss, Wolfgang Wurst, Patricia Ruiz Noppinger, and Harald von Melchner
Nucleic Acids Res. 2008; 36: e133. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette
Eugenio Sangiorgi, Zhang Shuhua, and Mario R. Capecchi
Nucleic Acids Res. 2008; 36: e134. [Abstract] [Full text] [Print PDF]  

Nucleic Acid Enzymes
Serial analysis of mutation spectra (SAMS): a new approach for the determination of mutation spectra of site-specific DNA damage and their sequence dependence
Huafeng Fang and John-Stephen Taylor
Nucleic Acids Res. 2008; 36: 6004-6012. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx)
Amy J. Baldwin, Kathy Busse, Alan M. Simm, and D. Dafydd Jones
Nucleic Acids Res. 2008; 36: e77. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Protein evolution by hypermutation and selection in the B cell line DT40
Hiroshi Arakawa, Hiroaki Kudo, Vera Batrak, Randolph B. Caldwell, Michael A. Rieger, Joachim W. Ellwart, and Jean-Marie Buerstedde
Nucleic Acids Res. 2008; 36: e1. [Abstract] [Full text] [Print PDF]  

Methods Online
Recombineering with tolC as a Selectable/Counter-selectable Marker: remodeling the rRNA Operons of Escherichia coli
Joseph A. DeVito
Nucleic Acids Res. 2008; 36: e4. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

[Next page]
Pages: 1 2 3 4 5 6 7 8 9

* Subspecialty Collections Home