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Nucleic acid structure


This category presents methods to analyze nucleic acid structure either indirectly (e.g. by chemical probing, using electrophoresis) or directly (e.g. using fluorescence, NMR or crystallography). Specific methods to prepare nucleic acid samples for structural analyses are also described.


Citations 31-40 of 59 total displayed.

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Methods Online
Thermal difference spectra: a specific signature for nucleic acid structures
Jean-Louis Mergny, Jing Li, Laurent Lacroix, Samir Amrane, and Jonathan B. Chaires
Nucleic Acids Res. 2005; 33: e138. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
An evolutionary intra-molecular shift in the preferred U3 snoRNA binding site on pre-ribosomal RNA
Anton V. Borovjagin and Susan A. Gerbi
Nucleic Acids Res. 2005; 33: 4995-5005. [Abstract] [Full text] [Print PDF]  

Methods Online
Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules
Lida K. Gifford, Joanna B. Opalinska, David Jordan, Vikram Pattanayak, Paul Greenham, Anna Kalota, Michelle Robbins, Kathy Vernovsky, Lesbeth C. Rodriguez, Bao T. Do, Ponzy Lu, and Alan M. Gewirtz
Nucleic Acids Res. 2005; 33: e28. [Abstract] [Full text] [Print PDF]  

Methods Online
Mapping the B-A conformational transition along plasmid DNA
Karel Nejedlý, Jana Chládková, Michaela Vorlícková, Iva Hrabcová, and Jaroslav Kypr
Nucleic Acids Res. 2005; 33: e5. [Abstract] [Full text] [Print PDF]  

Methods Online
Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies
Karen L. Buchmueller and Kevin M. Weeks
Nucleic Acids Res. 2004; 32: e184. [Abstract] [Full text] [Print PDF]  

Methods Online
Synthesis of unimolecularly circular G-quadruplexes as prospective molecular probes
Tianyan Zhou, Guoshu Chen, Yifan Wang, Qiang Zhang, Ming Yang, and Tianhu Li
Nucleic Acids Res. 2004; 32: e173. [Abstract] [Full text] [Print PDF]  

Articles
Method for direct discrimination of intra- and intermolecular hydrogen bonds, and characterization of the G(:A):G(:A):G(:A):G heptad, with scalar couplings across hydrogen bonds
Hidetsugu Sotoya, Akimasa Matsugami, Tetsuro Ikeda, Kiyoshi Ouhashi, Seiichi Uesugi, and Masato Katahira
Nucleic Acids Res. 2004; 32: 5113-5118. [Abstract] [Full text] [Print PDF]  

Methods Online
Effective and robust plasmid topology analysis and the subsequent characterization of the plasmid isoforms thereby observed
Michael J. Molloy, Valerie S. Hall, Susannah I. Bailey, Katharine J. Griffin, Jim Faulkner, and Mark Uden
Nucleic Acids Res. 2004; 32: e129. [Abstract] [Full text] [Print PDF]  

Methods Online
Semi-automated, single-band peak-fitting analysis of hydroxyl radical nucleic acid footprint autoradiograms for the quantitative analysis of transitions
Keiji Takamoto, Mark R. Chance, and Michael Brenowitz
Nucleic Acids Res. 2004; 32: e119. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
A genomic selection strategy to identify accessible and dimerization blocking targets in the 5'-UTR of HIV-1 RNA
Martin R. Jakobsen, Christian K. Damgaard, Ebbe S. Andersen, Anna Podhajska, and Jørgen Kjems
Nucleic Acids Res. 2004; 32: e67. [Abstract] [Full text] [Print PDF]  

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