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Nucleic acid structure


This category presents methods to analyze nucleic acid structure either indirectly (e.g. by chemical probing, using electrophoresis) or directly (e.g. using fluorescence, NMR or crystallography). Specific methods to prepare nucleic acid samples for structural analyses are also described.

Citations 51-59 of 59 total displayed.

Past content

NAR Methods Online
Novel display of knotted DNA molecules by two-dimensional gel electrophoresis
Sonia Trigueros, Javier Arsuaga, Maria E. Vazquez, De Witt Sumners, and Joaquim Roca
Nucleic Acids Res. 2001; 29: e67. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Detection of competing DNA structures by thermal gradient gel electrophoresis: from self-association to triple helix formation by (G,A)-containing oligonucleotides
Paola B. Arimondo, Thérèse Garestier, Claude Hélène, and Jian-Sheng Sun
Nucleic Acids Res. 2001; 29: e15. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Efficient construction of long DNA duplexes with internal non-Watson–Crick motifs and modifications
Xiaofeng Zheng and Philip C. Bevilacqua
Nucleic Acids Res. 2001; 29: e6. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
End-specific covalent photo-dependent immobilisation of synthetic DNA to paramagnetic beads
Robert Penchovsky, E. Birch-Hirschfeld, and John S. McCaskill
Nucleic Acids Res. 2000; 28: e98. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Discriminating duplex and hairpin oligonucleotides using chemical shifts: application to the anticodon stem–loop of Escherichia coli tRNAPhe
J. Cabello-Villegas and E. P. Nikonowicz
Nucleic Acids Res. 2000; 28: e74. [Abstract] [Full text] [Print PDF]  

NAR Methods Online
Advanced method for oligonucleotide deprotection
Sergey A. Surzhikov, Edward N. Timofeev, Boris K. Chernov, Julia B. Golova, and Andrei D. Mirzabekov
Nucleic Acids Res. 2000; 28: e29. [Abstract] [Full text] [Print PDF]  

Articles
Improved quantitation of DNA curvature using ligation ladders
ED Ross, RB Den, PR Hardwidge, and LJ Maher, 3rd
Nucleic Acids Res. 1999; 27: 4135-4142. [Abstract] [Full text] [Print PDF]  

Articles
Visualizing tertiary folding of RNA and RNA-protein interactions by a tethered iron chelate: analysis ofHIV-1 Tat-TAR complex
I Huq, N Tamilarasu, and TM Rana
Nucleic Acids Res. 1999; 27: 1084-1093. [Abstract] [Full text] [Print PDF]  

Articles
A DNA polymerase stop assay for G-quadruplex-interactive compounds
H Han, LH Hurley, and M Salazar
Nucleic Acids Res. 1999; 27: 537-542. [Abstract] [Full text] [Print PDF]  

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