Targeted inhibition of gene function

Citations 1-10 of 68 total displayed.

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Chemistry
Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences

Takumi Ishizuka, Junya Yoshida, Yoji Yamamoto, Jun Sumaoka, Tullia Tedeschi, Roberto Corradini, Stefano Sforza, and Makoto Komiyama
Nucleic Acids Res. 2008; 36: 1464-1471. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Past content

Methods Online
Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon

Takuma Gondai, Kazuya Yamaguchi, Naoko Miyano-Kurosaki, Yuichirou Habu, and Hiroshi Takaku
Nucleic Acids Res. 2008; 36: e18. [Abstract] [Full text] [Print PDF]  

Methods Online
siRNA nanoformulation against the Ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma

Henri de Martimprey, Jean-Remi Bertrand, Alfredo Fusco, Massimo Santoro, Patrick Couvreur, Christine Vauthier, and Claude Malvy
Nucleic Acids Res. 2008; 36: e2. [Abstract] [Full text] [Print PDF]  

Methods Online
Comprehensive viral oligonucleotide probe design using conserved protein regions

Omar J. Jabado, Yang Liu, Sean Conlan, P. Lan Quan, Hédi Hegyi, Yves Lussier, Thomas Briese, Gustavo Palacios, and W. I. Lipkin
Nucleic Acids Res. 2008; 36: e3. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

Michaela Scherr, Letizia Venturini, Karin Battmer, Michael Schaller-Schoenitz, Daniel Schaefer, Iris Dallmann, Arnold Ganser, and Matthias Eder
Nucleic Acids Res. 2007; 35: e149. [Abstract] [Full text] [Print PDF]  

RNA
Improved silencing properties using small internally segmented interfering RNAs

Jesper B. Bramsen, Maria B. Laursen, Christian K. Damgaard, Suzy W. Lena, B. Ravindra Babu, Jesper Wengel, and Jørgen Kjems
Nucleic Acids Res. 2007; 35: 5886-5897. [Abstract] [Full text] [Print PDF]  

Methods Online
Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities

Masatoshi Ichihara, Yoshiki Murakumo, Akio Masuda, Toru Matsuura, Naoya Asai, Mayumi Jijiwa, Maki Ishida, Jun Shinmi, Hiroshi Yatsuya, Shanlou Qiao, Masahide Takahashi, and Kinji Ohno
Nucleic Acids Res. 2007; 35: e123. [Abstract] [Full text] [Print PDF] [ Supplementary Data ] [ Supplementary Data ]  

Methods Online
Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference

Christiane Hitz, Wolfgang Wurst, and Ralf Kühn
Nucleic Acids Res. 2007; 35: e90. [Abstract] [Full text] [Print PDF]  

Methods Online
A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain

Zahra Hassani, Jean-Christophe François, Gladys Alfama, Ghislaine Morvan Dubois, Mathilde Paris, Carine Giovannangeli, and Barbara A. Demeneix
Nucleic Acids Res. 2007; 35: e65. [Abstract] [Full text] [Print PDF]  

Methods Online
Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines

Jørn R. Henriksen, Cecilie Løkke, Martin Hammerø, Dirk Geerts, Rogier Versteeg, Trond Flægstad, and Christer Einvik
Nucleic Acids Res. 2007; 35: e67. [Abstract] [Full text] [Print PDF]  

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