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Targeted inhibition of gene function
This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.
Citations 1-10 of 91 total displayed.
- Methods Online
RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs
- Lindsey L. Snyder, Iqbal Ahmed, and Laura F. Steel
Nucleic Acids Res. 2009; 37: e127.
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- Methods Online
Gene silencing in the marine diatom Phaeodactylum tricornutum
- Valentina De Riso, Raffaella Raniello, Florian Maumus, Alessandra Rogato, Chris Bowler, and Angela Falciatore
Nucleic Acids Res. 2009; 37: e96.
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- Methods Online
Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells
- Mark Johnson, Hui Hui Phua, Sophia C. Bennett, Jennifer M. Spence, and Christine J. Farr
Nucleic Acids Res. 2009; 37: e98.
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- Methods Online
Conditional gene silencing of multiple genes with antisense RNAs and generation of a mutator strain of Escherichia coli
- Nobutaka Nakashima and Tomohiro Tamura
Nucleic Acids Res. 2009; 37: e103.
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- Methods Online
p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication
- Engin Gürlevik, Norman Woller, Peter Schache, Nisar P. Malek, Thomas C. Wirth, Lars Zender, Michael P. Manns, Stefan Kubicka, and Florian Kühnel
Nucleic Acids Res. 2009; 37: e84.
[Abstract]
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- Methods Online
Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles
- Abdullah Ely, Tanusha Naidoo, and Patrick Arbuthnot
Nucleic Acids Res. 2009; 37: e91.
[Abstract]
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- Methods Online
A novel method for tissue-specific RNAi rescue in Drosophila
- Joachim G. Schulz, Guido David, and Bassem A. Hassan
Nucleic Acids Res. 2009; 37: e93.
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- Methods Online
Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
- Takeshi Haraguchi, Yuka Ozaki, and Hideo Iba
Nucleic Acids Res. 2009; 37: e43.
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- Methods Online
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci
- Ina Weidenfeld, Manfred Gossen, Rainer Löw, David Kentner, Stefan Berger, Dirk Görlich, Dusan Bartsch, Hermann Bujard, and Kai Schönig
Nucleic Acids Res. 2009; 37: e50.
[Abstract]
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- Methods Online
Detection of siRNA administered to cells and animals by using a fluorescence intensity distribution analysis polarization system
- Takashi Abe, Kazuhito Goda, Kazunobu Futami, and Yasuhiro Furuichi
Nucleic Acids Res. 2009; 37: e56.
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