Skip Navigation

Targeted inhibition of gene function


This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.


Citations 1-10 of 91 total displayed.

Most recent content

Methods Online
RNA polymerase III can drive polycistronic expression of functional interfering RNAs designed to resemble microRNAs
Lindsey L. Snyder, Iqbal Ahmed, and Laura F. Steel
Nucleic Acids Res. 2009; 37: e127. [Abstract] [Full text] [Print PDF]  

Past content

Methods Online
Gene silencing in the marine diatom Phaeodactylum tricornutum
Valentina De Riso, Raffaella Raniello, Florian Maumus, Alessandra Rogato, Chris Bowler, and Angela Falciatore
Nucleic Acids Res. 2009; 37: e96. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells
Mark Johnson, Hui Hui Phua, Sophia C. Bennett, Jennifer M. Spence, and Christine J. Farr
Nucleic Acids Res. 2009; 37: e98. [Abstract] [Full text] [Print PDF]  

Methods Online
Conditional gene silencing of multiple genes with antisense RNAs and generation of a mutator strain of Escherichia coli
Nobutaka Nakashima and Tomohiro Tamura
Nucleic Acids Res. 2009; 37: e103. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
p53-dependent antiviral RNA-interference facilitates tumor-selective viral replication
Engin Gürlevik, Norman Woller, Peter Schache, Nisar P. Malek, Thomas C. Wirth, Lars Zender, Michael P. Manns, Stefan Kubicka, and Florian Kühnel
Nucleic Acids Res. 2009; 37: e84. [Abstract] [Full text] [Print PDF]  

Methods Online
Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles
Abdullah Ely, Tanusha Naidoo, and Patrick Arbuthnot
Nucleic Acids Res. 2009; 37: e91. [Abstract] [Full text] [Print PDF]  

Methods Online
A novel method for tissue-specific RNAi rescue in Drosophila
Joachim G. Schulz, Guido David, and Bassem A. Hassan
Nucleic Acids Res. 2009; 37: e93. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
Takeshi Haraguchi, Yuka Ozaki, and Hideo Iba
Nucleic Acids Res. 2009; 37: e43. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci
Ina Weidenfeld, Manfred Gossen, Rainer Löw, David Kentner, Stefan Berger, Dirk Görlich, Dusan Bartsch, Hermann Bujard, and Kai Schönig
Nucleic Acids Res. 2009; 37: e50. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Detection of siRNA administered to cells and animals by using a fluorescence intensity distribution analysis polarization system
Takashi Abe, Kazuhito Goda, Kazunobu Futami, and Yasuhiro Furuichi
Nucleic Acids Res. 2009; 37: e56. [Abstract] [Full text] [Print PDF]  

[Next page]
Pages: 1 2 3 4 5 6 7 8 9 10

* Subspecialty Collections Home