Targeted inhibition of gene function

Citations 11-20 of 91 total displayed.

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Methods Online
A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells

Melanie I. Trombly, Hong Su, and Xiaozhong Wang
Nucleic Acids Res. 2009; 37: e34. [Abstract] [Full text] [Print PDF]  

Methods Online
A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference

Yanjie Lu, Jiening Xiao, Huixian Lin, Yunlong Bai, Xiaobin Luo, Zhiguo Wang, and Baofeng Yang
Nucleic Acids Res. 2009; 37: e24. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Forward and robust selection of the most potent and noncellular toxic siRNAs from RNAi libraries

Zhen Li, Yves Fortin, and Shi-Hsiang Shen
Nucleic Acids Res. 2009; 37: e8. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Gene regulation, Chromatin and Epigenetics
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs

Xueping Yu, Jimmy Lin, Donald J. Zack, Joshua T. Mendell, and Jiang Qian
Nucleic Acids Res. 2008; 36: 6494-6503. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
Recombineering-mediated tagging of Drosophila genomic constructs for in vivo localization and acute protein inactivation

Koen J. T. Venken, Jaroslaw Kasprowicz, Sabine Kuenen, Jiekun Yan, Bassem A. Hassan, and Patrik Verstreken
Nucleic Acids Res. 2008; 36: e114. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

Methods Online
A functional selection of viral genetic elements in cultured cells to identify hepatitis C virus RNA translation inhibitors

Loic Jaffrelo, Sandrine Chabas, Sandrine Reigadas, Aude Pflieger, Czeslaw Wychowski, Julie Rumi, Michel Ventura, Jean-Jacques Toulmé, and Cathy Staedel
Nucleic Acids Res. 2008; 36: e95. [Abstract] [Full text] [Print PDF]  

Methods Online
Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch

David Greber, Marie Daoud El-Baba, and Martin Fussenegger
Nucleic Acids Res. 2008; 36: e101. [Abstract] [Full text] [Print PDF]  

Methods Online
Transduction of artificial transcriptional regulatory proteins into human cells

Chae-Ok Yun, Hyun-Chul Shin, Tae-Dong Kim, Wan-Hee Yoon, Yoon-A Kang, Heung-Sun Kwon, Seong Keun Kim, and Jin-Soo Kim
Nucleic Acids Res. 2008; 36: e103. [Abstract] [Full text] [Print PDF]  

Methods Online
Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus

Anna-Maria Anesti, Pieter J. Peeters, Ines Royaux, and Robert S. Coffin
Nucleic Acids Res. 2008; 36: e86. [Abstract] [Full text] [Print PDF]  

Molecular Biology
Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells

Takehiko Shiraishi, Ramin Hamzavi, and Peter E. Nielsen
Nucleic Acids Res. 2008; 36: 4424-4432. [Abstract] [Full text] [Print PDF] [ Supplementary Data ]  

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