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Targeted inhibition of gene function
This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.
Citations 41-50 of 91 total displayed.
- RNA
Translational control and target recognition by Escherichia coli small RNAs in vivo
- Johannes H. Urban and Jörg Vogel
Nucleic Acids Res. 2007; 35: 1018-1037.
[Abstract]
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- Methods Online
Development of a species-specific RNA polymerase I-based shRNA expression vector
- M. S. Brenz Verca, Peter Weber, Christine Mayer, Cornelia Graf, Damián Refojo, Ralf Kühn, Ingrid Grummt, and Beat Lutz
Nucleic Acids Res. 2007; 35: e10.
[Abstract]
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- Molecular Biology
Different modes and potencies of translational repression by sequence-specific RNAprotein interaction at the 5'-UTR
- Minghua Nie and Han Htun
Nucleic Acids Res. 2006; 34: 5528-5540.
[Abstract]
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- Molecular Biology
Specific binding of a hexanucleotide to HIV-1 reverse transcriptase: a novel class of bioactive molecules
- Alessandra Mescalchin, Winfried Wünsche, Sandra D. Laufer, Dina Grohmann, Tobias Restle, and Georg Sczakiel
Nucleic Acids Res. 2006; 34: 5631-5637.
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[ Supplementary Data ]
- Computational Biology
Rational design and rapid screening of antisense oligonucleotides for prokaryotic gene modulation
- Yu Shao, Yan Wu, Chi Yu Chan, Kathleen McDonough, and Ye Ding
Nucleic Acids Res. 2006; 34: 5660-5669.
[Abstract]
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- Methods Online
Paired termini stabilize antisense RNAs and enhance conditional gene silencing in Escherichia coli
- Nobutaka Nakashima, Tomohiro Tamura, and Liam Good
Nucleic Acids Res. 2006; 34: e138.
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[ Supplementary Data ]
- RNA
Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli
- Omid R. Faridani, Abbas Nikravesh, Deo Prakash Pandey, Kenn Gerdes, and Liam Good
Nucleic Acids Res. 2006; 34: 5915-5922.
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- Methods Online
Inducible microRNA expression by an all-in-one episomal vector system
- Alexey Epanchintsev, Peter Jung, Antje Menssen, and Heiko Hermeking
Nucleic Acids Res. 2006; 34: e119.
[Abstract]
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- Articles
Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs
- Aurel Strat, Lu Gao, Tada Utsuki, Bing Cheng, Sam Nuthalapaty, J. Mike Mathis, Yoshinobu Odaka, and Tony Giordano
Nucleic Acids Res. 2006; 34: 3803-3810.
[Abstract]
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[ Supplementary Data ]
- Methods Online
Aptamer mediated siRNA delivery
- Ted C. Chu, Karen Y. Twu, Andrew D. Ellington, and Matthew Levy
Nucleic Acids Res. 2006; 34: e73.
[Abstract]
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