Skip Navigation

Targeted inhibition of gene function


This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.


Citations 51-60 of 91 total displayed.

Past content

Methods Online
Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155
Kwan-Ho Chung, Christopher C. Hart, Sarmad Al-Bassam, Adam Avery, Jennifer Taylor, Paresh D. Patel, Anne B. Vojtek, and David L. Turner
Nucleic Acids Res. 2006; 34: e53. [Abstract] [Full text] [Print PDF]  

Methods Online
Thorough validation of siRNA-induced cell death phenotypes defines new anti-apoptotic protein
Weilin Wu, Emily Hodges, and Christer Höög
Nucleic Acids Res. 2006; 34: e13. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Quantum dots to monitor RNAi delivery and improve gene silencing
Alice A. Chen, Austin M. Derfus, Salman R. Khetani, and Sangeeta N. Bhatia
Nucleic Acids Res. 2005; 33: e190. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Articles
Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells
Huafeng Fang, Xuan Yue, Xiaoxu Li, and John-Stephen Taylor
Nucleic Acids Res. 2005; 33: 6700-6711. [Abstract] [Full text] [Print PDF]  

Methods Online
A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification
Ming Jiang, Andrey A. Arzumanov, Michael J. Gait, and Jo Milner
Nucleic Acids Res. 2005; 33: e151. [Abstract] [Full text] [Print PDF]  

Methods Online
Single small-interfering RNA expression vector for silencing multiple transforming growth factor-ß pathway components
Amarsanaa Jazag, Fumihiko Kanai, Hideaki Ijichi, Keisuke Tateishi, Tsuneo Ikenoue, Yasuo Tanaka, Miki Ohta, Jun Imamura, Bayasi Guleng, Yoshinari Asaoka, Takao Kawabe, Makoto Miyagishi, Kazunari Taira, and Masao Omata
Nucleic Acids Res. 2005; 33: e131. [Abstract] [Full text] [Print PDF]  

Methods Online
Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication
Ryan D. Egeland and Edwin M. Southern
Nucleic Acids Res. 2005; 33: e125. [Abstract] [Full text] [Print PDF]  

Articles
Functional polarity is introduced by Dicer processing of short substrate RNAs
Scott D. Rose, Dong-Ho Kim, Mohammed Amarzguioui, Jeremy D. Heidel, Michael A. Collingwood, Mark E. Davis, John J. Rossi, and Mark A. Behlke
Nucleic Acids Res. 2005; 33: 4140-4156. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

Methods Online
Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference
Xavier Coumoul, Vivek Shukla, Cuiling Li, Rui-Hong Wang, and Chu-Xia Deng
Nucleic Acids Res. 2005; 33: e102. [Abstract] [Full text] [Print PDF]  

Methods Online
A complementation method for functional analysis of mammalian genes
Juana Maria Gonzalez-Santos, Huibi Cao, Anan Wang, David R. Koehler, Bernard Martin, Roya Navab, and Jim Hu
Nucleic Acids Res. 2005; 33: e94. [Abstract] [Full text] [Print PDF] [ Supplementary Material ]  

[First page]   [Previous page]   [Next page]
Pages: 1 2 3 4 5 6 7 8 9 10

* Subspecialty Collections Home