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Targeted inhibition of gene function
This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.
Citations 51-60 of 91 total displayed.
- Methods Online
Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155
- Kwan-Ho Chung, Christopher C. Hart, Sarmad Al-Bassam, Adam Avery, Jennifer Taylor, Paresh D. Patel, Anne B. Vojtek, and David L. Turner
Nucleic Acids Res. 2006; 34: e53.
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- Methods Online
Thorough validation of siRNA-induced cell death phenotypes defines new anti-apoptotic protein
- Weilin Wu, Emily Hodges, and Christer Höög
Nucleic Acids Res. 2006; 34: e13.
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- Methods Online
Quantum dots to monitor RNAi delivery and improve gene silencing
- Alice A. Chen, Austin M. Derfus, Salman R. Khetani, and Sangeeta N. Bhatia
Nucleic Acids Res. 2005; 33: e190.
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- Articles
Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells
- Huafeng Fang, Xuan Yue, Xiaoxu Li, and John-Stephen Taylor
Nucleic Acids Res. 2005; 33: 6700-6711.
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- Methods Online
A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification
- Ming Jiang, Andrey A. Arzumanov, Michael J. Gait, and Jo Milner
Nucleic Acids Res. 2005; 33: e151.
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- Methods Online
Single small-interfering RNA expression vector for silencing multiple transforming growth factor-ß pathway components
- Amarsanaa Jazag, Fumihiko Kanai, Hideaki Ijichi, Keisuke Tateishi, Tsuneo Ikenoue, Yasuo Tanaka, Miki Ohta, Jun Imamura, Bayasi Guleng, Yoshinari Asaoka, Takao Kawabe, Makoto Miyagishi, Kazunari Taira, and Masao Omata
Nucleic Acids Res. 2005; 33: e131.
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- Methods Online
Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication
- Ryan D. Egeland and Edwin M. Southern
Nucleic Acids Res. 2005; 33: e125.
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- Articles
Functional polarity is introduced by Dicer processing of short substrate RNAs
- Scott D. Rose, Dong-Ho Kim, Mohammed Amarzguioui, Jeremy D. Heidel, Michael A. Collingwood, Mark E. Davis, John J. Rossi, and Mark A. Behlke
Nucleic Acids Res. 2005; 33: 4140-4156.
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- Methods Online
Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference
- Xavier Coumoul, Vivek Shukla, Cuiling Li, Rui-Hong Wang, and Chu-Xia Deng
Nucleic Acids Res. 2005; 33: e102.
[Abstract]
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- Methods Online
A complementation method for functional analysis of mammalian genes
- Juana Maria Gonzalez-Santos, Huibi Cao, Anan Wang, David R. Koehler, Bernard Martin, Roya Navab, and Jim Hu
Nucleic Acids Res. 2005; 33: e94.
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