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Targeted inhibition of gene function
This category covers new developments using RNA and oligonucleotide strategies for specific inhibition of gene function. Examples include antisense, ribozymes, triplex and RNAi.
Citations 61-70 of 91 total displayed.
- Methods Online
RNA interference by mixtures of siRNAs prepared using custom oligonucleotide arrays
- Andrew V. Oleinikov, Jun Zhao, and Matthew D. Gray
Nucleic Acids Res. 2005; 33: e92.
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- Methods Online
Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei
- Masakiyo Sakaguchi, Takamasa Nukui, Hiroyuki Sonegawa, Hitoshi Murata, Junichiro Futami, Hidenori Yamada, and Nam-ho Huh
Nucleic Acids Res. 2005; 33: e88.
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- Methods Online
Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels
- Heung-Sun Kwon, Hyun-Chul Shin, and Jin-Soo Kim
Nucleic Acids Res. 2005; 33: e74.
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- Methods Online
Single copy shRNA configuration for ubiquitous gene knockdown in mice
- Jost Seibler, Birgit Küter-Luks, Heidrun Kern, Sandra Streu, Leona Plum, Jan Mauer, Ralf Kühn, Jens C. Brüning, and Frieder Schwenk
Nucleic Acids Res. 2005; 33: e67.
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- Methods Online
An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi
- Hongxia Zhou, Xu Gang Xia, and Zuoshang Xu
Nucleic Acids Res. 2005; 33: e62.
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- Methods Online
L1 retrotransposon-mediated stable gene silencing
- Nuo Yang, Lin Zhang, and Haig H. Kazazian, Jr
Nucleic Acids Res. 2005; 33: e57.
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- Methods Online
siRNA target site secondary structure predictions using local stable substructures
- Bret S. E. Heale, Harris S. Soifer, Chauncey Bowers, and John J. Rossi
Nucleic Acids Res. 2005; 33: e30.
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- Methods Online
Dissecting RNA silencing in protoplasts uncovers novel effects of viral suppressors on the silencing pathway at the cellular level
- Yijun Qi, Xuehua Zhong, Asuka Itaya, and Biao Ding
Nucleic Acids Res. 2004; 32: e179.
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- Methods Online
RNA silencing in plants by the expression of siRNA duplexes
- Shanfa Lu, Rui Shi, Cheng-Chung Tsao, Xiaoping Yi, Laigeng Li, and Vincent L. Chiang
Nucleic Acids Res. 2004; 32: e171.
[Abstract]
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- Methods Online
Quantitative detection of siRNA and single-stranded oligonucleotides: relationship between uptake and biological activity of siRNA
- Marita Overhoff, Winfried Wünsche, and Georg Sczakiel
Nucleic Acids Res. 2004; 32: e170.
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