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Nucleic Acids Research, 1974, Vol. 1, No. 10 1343-1350
© 1974

Articles

Sites of cleavage by restriction enzymes in viral DNAs: comparison of observed and expected frequencies

R.A. Elton

Medical Research Council Virology Unit Church Street, Glasgow G11 5JR, UK

Received August 23, 1974. Observed frequencies of restriction enzyme cleavage in viral DNAs are compared to those expected from the cleavage site sequence and the known size and nearest neighbour frequencies of the DNAs. It is found that a number of significant deviations from expectation occur, and possible explanations are put forward.


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