Nucleic Acids Research, 1974, Vol. 1, No. 11 1573-1578
© 1974
Articles |
Internal structure of the chromatin subunit
MRC Laboratory of Molecular Biology Hills Road, Cambridge CB2 2QH, England
Received September 19, 1974. The digestion of chromatin in situ with DNase I reveals, after denaturation, a regular series of single stranded DNA fragments the lengths of which represent multiples of 10 bases. These experiments are compatible with the DNA being onthe outside of the chromatin subunit and suggest that the subunit structure itself contains repetitive structural elements. Possible models are discussed.
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