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Nucleic Acids Research, 1974, Vol. 1, No. 2 235-244
© 1974

Articles

Acceptor activity of hypermethylated E.coli tRNAfMet

L.P. Shershneva, T.V. Venkstern and A.A. Bayev

Institute of Molecular Biology, Academy of Sciences of the USSR Moscow, USSR

Received December 6, 1973. The acceptor activity of normal E.coli Formula was compared with that of a preparation with surplus methyl groups introduced by a crude methylase preparation from rat hepatoma. No changes in charging were detected when the aminoacylation was carried out in a homologous system. The data indicate that neither the surplus methyl groups by themselves, nor the eventual changes in spatial arrangement are essential for charging of E.coli Formula.


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