Skip Navigation

This Article
Right arrow Print PDF (357K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Ueyama, M.
Right arrow Articles by Kaneko, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ueyama, M.
Right arrow Articles by Kaneko, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1974, Vol. 1, No. 6 823-834
© 1974

Articles

A conformational study of some adenosines by use of nuclear Overhauser effect

M. Ueyama, K. Tori, M. Ikehara* and M. Kaneko

Shionogi Research Laboratory, Shionogi & Co., Ltd. Fukushima-ku, Osaka, 553 Japan

Received May 17, 1974.

Conformations of B-bromo-2'-O-triisopropylbenzenesulfonyladenosine Formula and its 3'-O-isomer Formula in solution have been determined by the use of intramolecular nuclear Overhauser effects in 1H NMR spectroscopy. Compound Formula has been proved to have a conformation in which the adenosine and benzene rings are intramolecularly stacked and compound Formula an elongated non-stacked conformation in dimethylsulphoxide. The 5'-O-acetyl derivative of Formula has also been found to adopt the intramolecularly stacked conformation in dimethylsulphoxide, but a non-stacked one in chloroform. Coupling constants observed are discussed in connection with the conformation of the ribose moiety. The 13C NMR spectra have also been examined, but no effect which could be ascribed to the stacking phenomena was observed in the carbon chemical shifts.

*Faculty of Pharmaceutical Sciences, Osaka University, Toneyama, Toyonaka, Osaka, 560 Japan


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
A. Mushtaq, M. Payton, and E. Sim
The COOH Terminus of Arylamine N-Acetyltransferase from Salmonella typhimurium Controls Enzymic Activity
J. Biol. Chem., March 29, 2002; 277(14): 12175 - 12181.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.