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Nucleic Acids Research, 1982, Vol. 10, No. 1 127-131
© 1982


Articles

Matrix program to analyze primary structure homology

Jiri Novotny

Cellular and Molecular Research Labratory, Massachusetts General Hospital, and Department of Pathology, Harvard Medical School Boston, MA 02114, USA

Received September 15, 1981. A FORTRAN program to analyze homology of letter strings (nucleotide or amino acid sequences) and to display the result in the form of a dot matrix is presented. The program is generally usable, user-friendly and has a number of options (filtering, "fudging," i.e., consideration of groups of homologous residues, and screening, i.e., display of only particular groups of residues) which greatly potentiate its analytical power.


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