Nucleic Acids Research, 1982, Vol. 10, No. 1 127-131
© 1982
Articles |
Matrix program to analyze primary structure homology
Cellular and Molecular Research Labratory, Massachusetts General Hospital, and Department of Pathology, Harvard Medical School Boston, MA 02114, USA
Received September 15, 1981. A FORTRAN program to analyze homology of letter strings (nucleotide or amino acid sequences) and to display the result in the form of a dot matrix is presented. The program is generally usable, user-friendly and has a number of options (filtering, "fudging," i.e., consideration of groups of homologous residues, and screening, i.e., display of only particular groups of residues) which greatly potentiate its analytical power.