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Nucleic Acids Research, 1982, Vol. 10, No. 1 141-156
© 1982

Articles

Codon preference and its use in identifying protein coding regions in long DNA sequences

R. Staden and A.D. McLachian

Laboratory of Molecular Biology The MRC Centre, Hills Road, Cambridge CB2 2QH, UK

Received September 16, 1981. This paper describes a computer method that uses codon preference to help find protein coding regions in long DNA sequences. The method can distinguish between introns and exons and can help to detect sequencing errors.


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