Nucleic Acids Research, 1982, Vol. 10, No. 24 7895-7903
© 1982
MOLECULAR BIOLOGY |
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line
Laboratoire de Geèneètique Mole`culaire des Eucaryotes du CNRS, Uniteè 184 de Biologie Moleèculaire et de Geènie Geèneètique de I'INSERM, Faculteè de Meèdecine 11 Rue Humann, 67085 Strasbourg Ceèdex, France
*to whom reprint requests should be sent
Received November 18, 1982. Accepted November 25, 1982.
cDNA clones corresponding to a mRNA whose level is rapidly increased by addition of oestradiol to the culture medium have been isolated by differential screening of a cDNA library from the breast cancer cell line MCF-7, which contains oestrogen receptors. Such clones will be useful in studies of the DNA sequences required for hormonal induction and to determine whether expression of the corresponding gene is in any way related to the cancerous state. We have also obtained a cDNA clone for a messenger whose level is apparently decreased by steroid hormones
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K. Roy, M. G. Egan, S. Sirlin, and F. M. Sirotnak Posttranscriptionally Mediated Decreases in Folylpolyglutamate Synthetase Gene Expression in Some Folate Analogue-resistant Variants of the L1210 Cell. EVIDENCE FOR AN ALTERED COGNATE mRNA IN THE VARIANTS AFFECTING THE RATE OF DE NOVO SYNTHESIS OF THE ENZYME J. Biol. Chem., March 14, 1997; 272(11): 6903 - 6908. [Abstract] [Full Text] [PDF]
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G. Sotiropoulou, A. Anisowicz, and R. Sager Identification, Cloning, and Characterization of Cystatin M, a Novel Cysteine Proteinase Inhibitor, Down-regulated in Breast Cancer J. Biol. Chem., January 10, 1997; 272(2): 903 - 910. [Abstract] [Full Text] [PDF]
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H. Mashimo, D.-C. Wu, D. K. Podolsky, and M. C. Fishman Impaired Defense of Intestinal Mucosa in Mice Lacking Intestinal Trefoil Factor Science, October 11, 1996; 274(5285): 262 - 265. [Abstract] [Full Text]
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K. Roy, K. Mitsugi, S. Sirlin, B. Shane, and F. M. Sirotnak Different Antifolate-resistant L1210 Cell Variants with either Increased or Decreased Folylpolyglutamate Synthetase Gene Expression at the Level of mRNA Transcription J. Biol. Chem., November 10, 1995; 270(45): 26918 - 26922. [Abstract] [Full Text] [PDF]
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M. B. Martin, P. Garcia-Morales, A. Stoica, H. B. Solomon, M. Pierce, D. Katz, S. Zhang, M. Danielsen, and M. Saceda Effects of 12-O-Tetradecanoylphorbol-13-acetate on Estrogen Receptor Activity in MCF-7 Cells J. Biol. Chem., October 20, 1995; 270(42): 25244 - 25251. [Abstract] [Full Text] [PDF]
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P Liang and A. Pardee Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction Science, August 14, 1992; 257(5072): 967 - 971. [Abstract] [PDF]
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M. Rio, J. Bellocq, J. Daniel, C Tomasetto, R Lathe, M. Chenard, A Batzenschlager, and P Chambon Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa Science, August 5, 1988; 241(4866): 705 - 708. [Abstract] [PDF]
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E. Raspe, H. Duez, P. Gervois, C. Fievet, J.-C. Fruchart, S. Besnard, J. Mariani, A. Tedgui, and B. Staels Transcriptional Regulation of Apolipoprotein C-III Gene Expression by the Orphan Nuclear Receptor RORalpha J. Biol. Chem., January 19, 2001; 276(4): 2865 - 2871. [Abstract] [Full Text] [PDF]
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P. Gervois, N. Vu-Dac, R. Kleemann, M. Kockx, G. Dubois, B. Laine, V. Kosykh, J.-C. Fruchart, T. Kooistra, and B. Staels Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor alpha Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein beta J. Biol. Chem., August 31, 2001; 276(36): 33471 - 33477. [Abstract] [Full Text] [PDF]
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E. R. Schuur, A. V. Loktev, M. Sharma, Z. Sun, R. A. Roth, and R. J. Weigel Ligand-dependent Interaction of Estrogen Receptor-alpha with Members of the Forkhead Transcription Factor Family J. Biol. Chem., August 31, 2001; 276(36): 33554 - 33560. [Abstract] [Full Text] [PDF]
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A. J. Butt, S. M. Firth, M. A. King, and R. C. Baxter Insulin-like Growth Factor-binding Protein-3 Modulates Expression of Bax and Bcl-2 and Potentiates p53-independent Radiation-induced Apoptosis in Human Breast Cancer Cells J. Biol. Chem., December 8, 2000; 275(50): 39174 - 39181. [Abstract] [Full Text] [PDF]
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F. Martelli, T. Hamilton, D. P. Silver, N. E. Sharpless, N. Bardeesy, M. Rokas, R. A. DePinho, D. M. Livingston, and S. R. Grossman p19ARF targets certain E2F species for degradation PNAS, April 10, 2001; 98(8): 4455 - 4460. [Abstract] [Full Text] [PDF]
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