Skip Navigation

This Article
Right arrow Print PDF (412K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (141)
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Huddleston, J. A.
Right arrow Articles by Brownlee, G. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Huddleston, J. A.
Right arrow Articles by Brownlee, G. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1982, Vol. 10, No. 3 1029-1038
© 1982

MOLECULAR BIOLOGY

The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68

J. A. Huddleston and G. G. Brownlee

Sir William Dunn School of Pathology, University of Oxford South Parks Road, Oxford OX1 3RE, UK

Received December 8, 1981. Accepted January 15, 1982.

The nucleotide sequence of the nucleoprotein gene of influenza A/NT/60/68 was established after using improved cloning methods to obtain full length cDNA clones in pBr322. The gene is 1565 residues long and codes for a basic protein of 498 amino acids. There are only 30 amino acid differences between it and the homologous sequence in A/PR/8/34, all occurring as point mutations. Assuming a common lineage, the evolutionary rate of divergence of the two strains is 0.18% amino acid per year. This confirms there is a slow but significant rate of evolution.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Gen. Virol.Home page
N. V. Makarova, N. V. Kaverin, S. Krauss, D. Senne, and R. G. Webster
Transmission of Eurasian avian H2 influenza virus to shorebirds in North America
J. Gen. Virol., December 1, 1999; 80(12): 3167 - 3171.
[Abstract] [Full Text]

Home page
 J. Virol.Home page
O. P. Zhirnov, T. E. Konakova, W. Garten, and H.-D. Klenk
Caspase-Dependent N-Terminal Cleavage of Influenza Virus Nucleocapsid Protein in Infected Cells
J. Virol., December 1, 1999; 73(12): 10158 - 10163.
[Abstract] [Full Text]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. Neumann, T. Watanabe, H. Ito, S. Watanabe, H. Goto, P. Gao, M. Hughes, D. R. Perez, R. Donis, E. Hoffmann, et al.
Generation of influenza A viruses entirely from cloned cDNAs
PNAS, August 3, 1999; 96(16): 9345 - 9350.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
A. Vines, K. Wells, M. Matrosovich, M. R. Castrucci, T. Ito, and Y. Kawaoka
The Role of Influenza A Virus Hemagglutinin Residues 226 and 228 in Receptor Specificity and Host Range Restriction
J. Virol., September 1, 1998; 72(9): 7626 - 7631.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Goto and Y. Kawaoka
A novel mechanism for the acquisition of virulence by a human influenza A virus
PNAS, August 18, 1998; 95(17): 10224 - 10228.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.