Skip Navigation

This Article
Right arrow Print PDF (331K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Gronenborn, A. M.
Right arrow Articles by McLaughlin, L. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gronenborn, A. M.
Right arrow Articles by McLaughlin, L. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1983, Vol. 11, No. 16 5691-5699
© 1983

CHEMISTRY

A nuclear magnetic resonance study of the ribotrinucleoside dlphophate UpUpC

Angela M. Gronenborn1, Barry J. Kimber1, G.Marius Clore1 and Larry W. McLaughlin2

1Division of Molecular Pharmacology, National Institute for Medical Research Mill Hill, London NW7 1AA, UK 2Max-Planck-Institut f{euro}r Experimentelle Medizin Abteilung Chernie, Hennann-Rein Strasse 3, D-3400 Gottingen, FRG

Received June 23, 1983. Accepted July 28, 1983.

500 MHz 1H, 67.89 MHz 13C and 80.97 MHZ 31P-NMR studies are reported on the ribotrinucleoside diphosphate UpUpC, the triplet codon corresponding to the amino acid phenylalanine. Complete spectral assignments are given and con-formational parameters for the backbone and the furanose rings are determined. All three nucleotide units show a near-balance for the N/S equilibrium with a slight preference for the N-type ribose ({sum}60%) . The backbone conformation around the C3'-03' bonds show a preference for the trans domain, while the orientation aroung the C5'-05' bonds is predominantly trans.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.