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Nucleic Acids Research, 1983, Vol. 11, No. 18 6157-6166
© 1983

MOLECULAR BIOLOGY

Nucleotide sequence of the promoter region of the E. coli lysC gene

Michel Cassan, Jeanine Ronceray and Jean Claude Patte

Institut de Microbiologie, Université Paris-Sud, Centre d'Orsay 91405 Orsay Cedex, France

Received August 2, 1983. Accepted September 5, 1983.

The regulatory region of the lysC gene (that encodes the lysine-sensitive aspartokinase of Escherichia coli) has been identified and purified by the use of lysC-lacZ fusions. Its regulatory sequence has been determined. No signals simifaF to those described in the case of an attenuation mechanism could be found in the long leader sequence existing between the starts of transcription and of translation.


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