Nucleic Acids Research, 1983, Vol. 11, No. 21 7317-7330
© 1983
MOLECULAR BIOLOGY |
Sequence of 3,687 nudeotides from the 3' end of Sendai virus genome RNA and the predicted amino add sequences of viral NP, P and C proteins
Dept. Viral Infection, Institute of Medical Science, University of Tokyo Minato-ku, Tokyo 108 1Dept. Microbiology, Faculty of Medicine, University of Tokyo 2Dept. Physiological Chemistry, Tokyo Metropolitan Institute of Medical Science Bunkyo-ku, Tokyo 113, Japan
*To whom correspondence should be addressed
Received September 19, 1983. Accepted October 12, 1983.
The sequence of 3,687 nucleotides from the 3' end of the Sendai virus genome (Z strain) was determined by a molecular cloning technique followed by rapid sequence analysis. Two large open reading frames, one consisting of 1,572 nucleotides and the other of 1,704 nucleotides, were observed in the region, that is OP-1 and OP-2 from the 31 end of the genome. The amino acid sequences of the gene products were predicted from the observed sequence. Determination of amino acid compositions of viral proteins, P, HN, Fo, NP and M, led us to conclude that NP and P are the gene products of OP-1 and OP-2, respectively. An additional open reading frame consisting of 612 nucleotides (OP-3) was discovered in the 3' most proximal region of OP-2. The predicted product of OP-3 was considered to be viral non-structural protein C. The leader sequence of 51 nucleotides at the 31 terminal of the genome and consensus sequences at 3' and 5' ends of each gene for proteins NP 4nd P were identified.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  A. K. Perry, E. K. Chow, J. B. Goodnough, W.-C. Yeh, and G. Cheng Differential Requirement for TANK-binding Kinase-1 in Type I Interferon Responses to Toll-like Receptor Activation and Viral Infection J. Exp. Med., June 21, 2004; 199(12): 1651 - 1658. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Gotoh, K. Takeuchi, T. Komatsu, and J. Yokoo The STAT2 Activation Process Is a Crucial Target of Sendai Virus C Protein for the Blockade of Alpha Interferon Signaling J. Virol., March 15, 2003; 77(6): 3360 - 3370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Vulliemoz and L. Roux Given the Opportunity, the Sendai Virus RNA-Dependent RNA Polymerase Could as Well Enter Its Template Internally J. Virol., July 17, 2002; 76(16): 7987 - 7995. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Liu, I. Mori, Md. J. Hossain, L. Dong, and Y. Kimura Peroral vaccination with a temperature-sensitive mutant of parainfluenza virus type 1 protects mice against respiratory challenge infection J. Gen. Virol., December 1, 2001; 82(12): 2889 - 2894. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Vulliémoz and L. Roux "Rule of Six": How Does the Sendai Virus RNA Polymerase Keep Count? J. Virol., May 15, 2001; 75(10): 4506 - 4518. [Abstract] [Full Text]
|
|
|
|
|
|
M. D. Baron and T. Barrett Rinderpest Viruses Lacking the C and V Proteins Show Specific Defects in Growth and Transcription of Viral RNAs J. Virol., March 15, 2000; 74(6): 2603 - 2611. [Abstract] [Full Text]
|
|
|
|
|
|
A. Kato, K. Kiyotani, M. K. Hasan, T. Shioda, Y. Sakai, T. Yoshida, and Y. Nagai Sendai Virus Gene Start Signals Are Not Equivalent in Reinitiation Capacity: Moderation at the Fusion Protein Gene J. Virol., November 1, 1999; 73(11): 9237 - 9246. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Tapparel, D. Maurice, and L. Roux The Activity of Sendai Virus Genomic and Antigenomic Promoters Requires a Second Element Past the Leader Template Regions: a Motif (GNNNNN)3 Is Essential for Replication J. Virol., April 1, 1998; 72(4): 3117 - 3128. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K C Gupta and X Xu Facile PCR cloning of full-length Sendai virus mRNAs. Genome Res., May 1, 1992; 1(4): 293 - 296. [PDF]
|
|