Nucleic Acids Research, 1983, Vol. 11, No. 23 8287-8301
© 1983
MOLECULAR BIOLOGY |
The nucleotide sequence of the chick cytoplasmic ß-actin gene
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
Received August 24, 1983. Revised November 4, 1983. Accepted November 4, 1983.
The nudeotide sequence of the chick ß-actin gene was determined. The gene contains 5 introns; 4 interrupt the translated region at codons 41/42, 120/122, 267, 327/328 and a large intron occurs in the 5' untranslated region. The gene has a 97 nudeotide 5 '-untrtranslated region and a 594 nudeotide 3'-untranslated region. A slight heterogeneity in the position of the poly A addition site exists; polyadenylation can occur at either of two positions two nucleotides apart. The gene codes for an mRNA of 1814 or 1816 nucleotides, excluding the poly(A) tail. In contrast to the chicle skeletal muscle actin gene the ß-actin gene lacks the Cys codon between the initiator ATG and the codon for the N-terminal amino acid of the mature protein. la the 5' flanking DNA, 15 nucleotides downstream from the CCAAT sequence, is a tract of 25 nucleotides that is highly homologous to the sequence found in the same region of the rat ß-actin gene.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  S. C. Das, N. Isobe, M. Nishibori, and Y. Yoshimura Expression of transforming growth factor-{beta} isoforms and their receptors in utero-vaginal junction of hen oviduct in presence or absence of resident sperm with reference to sperm storage. Reproduction, November 1, 2006; 132(5): 781 - 790. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Mukudai, S. Kubota, T. Eguchi, S. Kondo, K. Nakao, and M. Takigawa Regulation of Chicken ccn2 Gene by Interaction between RNA cis-Element and Putative trans-Factor during Differentiation of Chondrocytes J. Biol. Chem., February 4, 2005; 280(5): 3166 - 3177. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Oh-hora, S. Johmura, A. Hashimoto, M. Hikida, and T. Kurosaki Requirement for Ras Guanine Nucleotide Releasing Protein 3 in Coupling Phospholipase C-{gamma}2 to Ras in B Cell Receptor Signaling J. Exp. Med., December 15, 2003; 198(12): 1841 - 1851. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Griffin, G. Flouriot, P. Sharp, G. Greene, and F. Gannon Distribution Analysis of the Two Chicken Estrogen Receptor-Alpha Isoforms and Their Transcripts in the Hypothalamus and Anterior Pituitary Gland Biol Reprod, October 1, 2001; 65(4): 1156 - 1163. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. S. Parcells, S.-F. Lin, R. L. Dienglewicz, V. Majerciak, D. R. Robinson, H.-C. Chen, Z. Wu, G. R. Dubyak, P. Brunovskis, H. D. Hunt, et al. Marek's Disease Virus (MDV) Encodes an Interleukin-8 Homolog (vIL-8): Characterization of the vIL-8 Protein and a vIL-8 Deletion Mutant MDV J. Virol., June 1, 2001; 75(11): 5159 - 5173. [Abstract] [Full Text]
|
|
|
|
 |
|
 B. A. Imhof, D. Dunon, D. Courtois, M. Luhtala, and O. Vainio Intestinal CD8{alpha}{alpha} and CD8{alpha}{beta} Intraepithelial Lymphocytes Are Thymus Derived and Exhibit Subtle Differences in TCR{beta} Repertoires J. Immunol., December 15, 2000; 165(12): 6716 - 6722. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Fujii, M. F. T. Escaño, K. Ishibashi, M. Fujii, Y. Sekiya, M. Yamamoto, and K. Saijoh Differential Expression of Neuroendocrine-Specific Protein in Form-Deprived Chick Eyes Invest. Ophthalmol. Vis. Sci., May 1, 2000; 41(6): 1533 - 1541. [Abstract] [Full Text]
|
|
|
|
 |
|
 C. Nerlov, E. Querfurth, H. Kulessa, and T. Graf GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription Blood, April 15, 2000; 95(8): 2543 - 2551. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. You, H. Kim, C.-C. Hsu, M. E. El Halawani, and D. N. Foster Three Different Turkey Luteinizing Hormone Receptor (tLH-R) Isoforms I: Characterization of Alternatively Spliced tLH-R Isoforms and Their Regulated Expression in Diverse Tissues Biol Reprod, January 1, 2000; 62(1): 108 - 116. [Abstract] [Full Text]
|
|
|
|
|
|
S. You, H. Kim, M. E. El Halawani, and D. N. Foster Three Different Turkey Luteinizing Hormone Receptor (tLH-R) Isoforms II: Characterization of Differentially Regulated tLH-R Messenger Ribonucleic Acid Isoforms in the Ovary Biol Reprod, January 1, 2000; 62(1): 117 - 124. [Abstract] [Full Text]
|
|
|
|
 |
|
 K. Yagami, J.-Y. Suh, M. Enomoto-Iwamoto, E. Koyama, W. R. Abrams, I. M. Shapiro, M. Pacifici, and M. Iwamoto Matrix GLA Protein Is a Developmental Regulator of Chondrocyte Mineralization and, When Constitutively Expressed, Blocks Endochondral and Intramembranous Ossification in the Limb J. Cell Biol., November 29, 1999; 147(5): 1097 - 1108. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Bernard, G. E. Bentley, J. Balthazart, F. W. Turek, and G. F. Ball Androgen Receptor, Estrogen Receptor {alpha}, and Estrogen Receptor {beta} Show Distinct Patterns of Expression in Forebrain Song Control Nuclei of European Starlings Endocrinology, October 1, 1999; 140(10): 4633 - 4643. [Abstract] [Full Text]
|
|
|
|
|
|
A. Seiler-Tuyns, N. Dufour, and F. Spertini Human Tumor Necrosis Factor-alpha Gene 3' Untranslated Region Confers Inducible Toxin Responsiveness to Homologous Promoter in Monocytic THP-1 Cells J. Biol. Chem., July 30, 1999; 274(31): 21714 - 21718. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Madruga, N. Koritschoner, S. Diebold, S. Kurz, and M Zenke Polarised expression pattern of focal contact proteins in highly motile antigen presenting dendritic cells J. Cell Sci., January 6, 1999; 112(11): 1685 - 1696. [Abstract] [PDF]
|
|
|
|
|
|
A. Hashimoto, H. Okada, A. Jiang, M. Kurosaki, S. Greenberg, E. A. Clark, and T. Kurosaki Involvement of Guanosine Triphosphatases and Phospholipase C-gamma 2 in Extracellular Signal-regulated Kinase, c-Jun NH2-terminal Kinase, and p38 Mitogen-activated Protein Kinase Activation by the B Cell Antigen Receptor J. Exp. Med., October 5, 1998; 188(7): 1287 - 1295. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Esser, M. Lampugnani, M Corada, E Dejana, and W Risau Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells J. Cell Sci., January 7, 1998; 111(13): 1853 - 1865. [Abstract] [PDF]
|
|
|
|
|
|
W. K.-H. Meyer, P. Reichenbach, U. Schindler, E. Soldaini, and M. Nabholz Interaction of STAT5 Dimers on Two Low Affinity Binding Sites Mediates Interleukin 2 (IL-2) Stimulation of IL-2 Receptor alpha Gene Transcription J. Biol. Chem., December 12, 1997; 272(50): 31821 - 31828. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Dunon, D. Courtois, O. Vainio, A. Six, C.H. Chen, M.D. Cooper, J.P. Dangy, and B.A. Imhof Ontogeny of the Immune System: gamma /delta and alpha /beta T Cells Migrate from Thymus to the Periphery in Alternating Waves J. Exp. Med., October 6, 1997; 186(7): 977 - 988. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Bang, N Papalopulu, C Kintner, and M. Goulding Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm Development, January 5, 1997; 124(10): 2075 - 2085. [Abstract] [PDF]
|
|
|
|
|
|
J. A. Spencer and R. P. Misra Expression of the Serum Response Factor Gene Is Regulated by Serum Response Factor Binding Sites J. Biol. Chem., July 12, 1996; 271(28): 16535 - 16543. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Kent, S. Wheatley, J. Andrews, A. Sinclair, and P Koopman A male-specific role for SOX9 in vertebrate sex determination Development, January 9, 1996; 122(9): 2813 - 2822. [Abstract] [PDF]
|
|
|
|
|
|
J. Frade, E Marti, P Bovolenta, M. Rodriguez-Pena, D Perez-Garcia, H Rohrer, D Edgar, and A Rodriguez-Tebar Insulin-like growth factor-I stimulates neurogenesis in chick retina by regulating expression of the alpha 6 integrin subunit Development, January 8, 1996; 122(8): 2497 - 2506. [Abstract] [PDF]
|
|
|
|
|
|
E. Ikeda, M. G. Achen, G. Breier, and W. Risau Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells J. Biol. Chem., August 25, 1995; 270(34): 19761 - 19766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Sperisen, S. M. Wang, E. Soldaini, M. Pla, C. Rusterholz, P. Bucher, P. Corthésy, P. Reichenbach, and M. Nabholz Mouse Interleukin-2 Receptor [IMAGE] Gene Expression J. Biol. Chem., May 5, 1995; 270(18): 10743 - 10753. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G Wirl, M Hermann, P Ekblom, and R Fassler Mammary epithelial cell differentiation in vitro is regulated by an interplay of EGF action and tenascin-C downregulation J. Cell Sci., January 6, 1995; 108(6): 2445 - 2456. [Abstract] [PDF]
|
|
|
|
 |
|
 N Kraut, J Frampton, K M McNagny, and T Graf A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets. Genes & Dev., January 1, 1994; 8(1): 33 - 44. [Abstract] [PDF]
|
|
|
|
|
|
E Ulrich, G Boehmelt, A Bird, and H Beug Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation. Genes & Dev., May 1, 1992; 6(5): 876 - 887. [Abstract] [PDF]
|
|
|
|
 |
|
 P Sperisen, S M Wang, P Reichenbach, and M Nabholz A PCR-based assay for reporter gene expression. Genome Res., February 1, 1992; 1(3): 164 - 170. [Abstract] [PDF]
|
|
|
|
|
|
A Trumpp, P A Blundell, J L de la Pompa, and R Zeller The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes & Dev., January 1, 1992; 6(1): 14 - 28. [Abstract] [PDF]
|
|
|
|
 |
|
 M Matsuoka, F Nagawa, K Okazaki, L Kingsbury, K Yoshida, U Muller, D. Larue, J. Winer, and H Sakano Detection of somatic DNA recombination in the transgenic mouse brain Science, October 4, 1991; 254(5028): 81 - 86. [Abstract] [PDF]
|
|