Skip Navigation

This Article
Right arrow Print PDF (363K)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Commercial Re-use Guidelines
for Open Access NAR Content
Google Scholar
Right arrow Articles by Meek, D. W.
Right arrow Articles by Hayward, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Meek, D. W.
Right arrow Articles by Hayward, R. S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nucleic Acids Research, 1984, Vol. 12, No. 14 5813-5821
© 1984

Articles

Nudeotide sequenee of the rpoA-rplQ DNA of Escherichia coli: a second regulalory binding site for protein S4?

David W. Meek and Richard S. Hayward

Department of Molecular Biology, University of Edinburgh Mayfield Road, Edinburgh EH9 31R, UK

Received May 17, 1984. Accepted June 21, 1984.

The "{alpha}-operon" of E.coli is a unit of regulation comprising the following known genes, mostly encoding ribosomal proteins (In order of transcription, and with their products named in brackets): rpsm (S13), rpsK (S11), rpsD (S4), rpoA ({alpha}-subunit of RNA polymerase), rplQ (L17). There is evidence that S4 tightly regulates all of these genes, except rpoA, by repressing translation of the polycistronic mRNA. Binding of S4 to the S13 start-site is thought to regulate the first three genes. We have extended the‘rpsD–rpoA’ sequences previously determined by others, to include allrpoA and rplQ. The rpoA–rplQ intercistronic region shows strong primary, and potential secondary structural homologies with the S4-binding sites on 16S rRNA and S13 mRNA. We suggest that S4 represses L17 translation directly.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Microbiol. Mol. Biol. Rev.Home page
M. K. B. Berlyn
Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map
Microbiol. Mol. Biol. Rev., September 1, 1998; 62(3): 814 - 984.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Yao, K. Yamamoto, Y. Nishi, Y. Nogi, and M. Muramatsu
Mouse RNA Polymerase I 16-kDa Subunit Able to Associate with 40-kDa Subunit Is a Homolog of Yeast AC19 Subunit of RNA Polymerases I and III
J. Biol. Chem., December 20, 1996; 271(51): 32881 - 32885.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.