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Nucleic Acids Research, 1984, Vol. 12, No. 15 6063-6072
© 1984

MOLECULAR BIOLOGY

Molecular cloning and chromosome assignment of murine N-ras

James Ryan1, Charles P. Hart2 and Frank Ruddle1,2

1Department of Human Genetics, Yale University New Haven, CT 06511, USA 2Department of Biology, Yale University New Haven, CT 06511, USA

Received May 18, 1984. Accepted July 3, 1984.

The murine N-ras gene was cloned by screening an ENBL-3 recombinant phage library with a human N-ras specific probe. Hybridization of two separate unique sequence N-ras probes, isolated from the 5' and 3' flanking sequences of the murine gene, to a mouse-Chinese hamster hybrid mapping panel assigns the N-ras locus to mouse chromosome three.


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