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Nucleic Acids Research, 1984, Vol. 12, No. 19 7285-7292
© 1984

CHEMISTRY

‘Interactive’ recognition in EcoRl restriction enzyme-DNA complex

Rosalind Kim, Paul Modrich* and Sung-Hou Kim

Department of Chemistry and Lawrence Berkeley Laboratory, University of California Berkeley, CA 94720, USA *Department of Biochemistry, Duke University Medical Center Durham, NC 27710, USA

Received September 11, 1984. Accepted September 19, 1984.

A solution study or interaction between DNA and EcoRI restriction enzyme snows that there is a definite distortion of DNA in the specific recognition complexes but no Measurable DNA distortion in the non-specific interaction.


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