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Nucleic Acids Research, 1984, Vol. 12, No. 1Part1 11-29
© 1984

MAIN-FRAME COMPUTERS

Intelligent computational assistance for experiment design

René Bach, Yumi Iwasaki1 and Peter Friedland

MOLGEN Project, Computer Science Department, Stanford University Stanford, CA 94305, USA

Received August 26, 1983.

We have developed an automated system for the design of laboratory experiments in molecular biology. The system uses a planning method known as skeletal plan refinement that attempts to emulate the human cognitive task of experiment design. This paper describes the theory, history, and implementation of the design system and illustrates its function in the domain of DNA cloning experiments.

1Current address: Teknowledge, Inc., 525 University Avenue, Palo Alto, CA 94301, USA


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